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Correction of human phospholamban R14del mutation associated with cardiomyopathy using targeted nucleases and combination therapy.
Karakikes, Ioannis; Stillitano, Francesca; Nonnenmacher, Mathieu; Tzimas, Christos; Sanoudou, Despina; Termglinchan, Vittavat; Kong, Chi-Wing; Rushing, Stephanie; Hansen, Jens; Ceholski, Delaine; Kolokathis, Fotis; Kremastinos, Dimitrios; Katoulis, Alexandros; Ren, Lihuan; Cohen, Ninette; Gho, Johannes M I H; Tsiapras, Dimitrios; Vink, Aryan; Wu, Joseph C; Asselbergs, Folkert W; Li, Ronald A; Hulot, Jean-Sebastien; Kranias, Evangelia G; Hajjar, Roger J.
Afiliação
  • Karakikes I; Cardiovascular Research Center, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.
  • Stillitano F; Department of Medicine, Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, California 94305, USA.
  • Nonnenmacher M; Stanford Cardiovascular Institute, Stanford University School of Medicine, Stanford, California 94305, USA.
  • Tzimas C; Cardiovascular Research Center, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.
  • Sanoudou D; Cardiovascular Research Center, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.
  • Termglinchan V; Molecular Biology, Biomedical Research Foundation of the Academy of Athens, Athens, Greece.
  • Kong CW; Pharmacology Department, University of Athens, Athens, Greece.
  • Rushing S; Department of Medicine, Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, California 94305, USA.
  • Hansen J; Stanford Cardiovascular Institute, Stanford University School of Medicine, Stanford, California 94305, USA.
  • Ceholski D; Stem Cell &Regenerative Medicine Consortium, Department of Physiology, LKS Faculty of Medicine, University of Hong Kong, Hong Kong, China.
  • Kolokathis F; Cardiovascular Research Center, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.
  • Kremastinos D; Department of Pharmacology and Systems Therapeutics, Systems Biology Center New York, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.
  • Katoulis A; Cardiovascular Research Center, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.
  • Ren L; Attikon Hospital, University of Athens, Athens 12462, Greece.
  • Cohen N; Attikon Hospital, University of Athens, Athens 12462, Greece.
  • Gho JMIH; Attikon Hospital, University of Athens, Athens 12462, Greece.
  • Tsiapras D; Stem Cell &Regenerative Medicine Consortium, Department of Physiology, LKS Faculty of Medicine, University of Hong Kong, Hong Kong, China.
  • Vink A; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.
  • Wu JC; Department of Cardiology, Division Heart and Lungs, University Medical Centre Utrecht, PO Box 85500, 3508 GA, Utrecht, The Netherlands.
  • Asselbergs FW; Ona ssis Cardiac Surgery Center, Athens, Greece.
  • Li RA; Department of Pathology, Division Laboratories and Pharmacy, University Medical Center Utrecht, PO Box 85500, 3508 GA, Utrecht, The Netherlands.
  • Hulot JS; Department of Medicine, Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, California 94305, USA.
  • Kranias EG; Stanford Cardiovascular Institute, Stanford University School of Medicine, Stanford, California 94305, USA.
  • Hajjar RJ; Department of Cardiology, Division Heart and Lungs, University Medical Centre Utrecht, PO Box 85500, 3508 GA, Utrecht, The Netherlands.
Nat Commun ; 6: 6955, 2015 Apr 29.
Article em En | MEDLINE | ID: mdl-25923014
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas de Ligação ao Cálcio / Miócitos Cardíacos / Reparo Gênico Alvo-Dirigido / Cardiomiopatias Idioma: En Ano de publicação: 2015 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas de Ligação ao Cálcio / Miócitos Cardíacos / Reparo Gênico Alvo-Dirigido / Cardiomiopatias Idioma: En Ano de publicação: 2015 Tipo de documento: Article