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Targeted deep sequencing of mucinous ovarian tumors reveals multiple overlapping RAS-pathway activating mutations in borderline and cancerous neoplasms.
Mackenzie, Robertson; Kommoss, Stefan; Winterhoff, Boris J; Kipp, Benjamin R; Garcia, Joaquin J; Voss, Jesse; Halling, Kevin; Karnezis, Anthony; Senz, Janine; Yang, Winnie; Prigge, Elena-Sophie; Reuschenbach, Miriam; Doeberitz, Magnus Von Knebel; Gilks, Blake C; Huntsman, David G; Bakkum-Gamez, Jamie; McAlpine, Jessica N; Anglesio, Michael S.
Afiliação
  • Mackenzie R; Molecular Oncology, BC Cancer Agency Research Centre, Vancouver, Canada. rmackenzie@bccrc.ca.
  • Kommoss S; Pathology and Laboratory Medicine, University of British Columbia, Vancouver, Canada. stefan.kommoss@med.uni-tuebingen.de.
  • Winterhoff BJ; Gynecology and Obstetrics, Tuebingen University Hospital, Tuebingen, Germany. stefan.kommoss@med.uni-tuebingen.de.
  • Kipp BR; Laboratory Medicine and Pathology, Mayo Clinic, Rochester, USA. bwinterhoff@hotmail.com.
  • Garcia JJ; Laboratory Medicine and Pathology, Mayo Clinic, Rochester, USA. Kipp.Benjamin@mayo.edu.
  • Voss J; Laboratory Medicine and Pathology, Mayo Clinic, Rochester, USA. garcia.joaquin@mayo.edu.
  • Halling K; Laboratory Medicine and Pathology, Mayo Clinic, Rochester, USA. Voss.Jesse@mayo.edu.
  • Karnezis A; Laboratory Medicine and Pathology, Mayo Clinic, Rochester, USA. Halling.Kevin@mayo.edu.
  • Senz J; Pathology and Laboratory Medicine, University of British Columbia, Vancouver, Canada. akarnezis@bccrc.ca.
  • Yang W; Pathology and Laboratory Medicine, University of British Columbia, Vancouver, Canada. Janine.Senz@vch.ca.
  • Prigge ES; Molecular Oncology, BC Cancer Agency Research Centre, Vancouver, Canada. wyang@bccrc.ca.
  • Reuschenbach M; Applied Tumor Biology, Institute of Pathology, University of Heidelberg, Heidelberg, Germany. elena.prigge@med.uni-heidelberg.de.
  • Doeberitz MV; Applied Tumor Biology, Institute of Pathology, University of Heidelberg, Heidelberg, Germany. miriam.reuschenbach@med.uni-heidelberg.de.
  • Gilks BC; Applied Tumor Biology, Institute of Pathology, University of Heidelberg, Heidelberg, Germany. knebel@med.uni-heidelberg.de.
  • Huntsman DG; Pathology and Laboratory Medicine, University of British Columbia, Vancouver, Canada. Blake.Gilks@vch.ca.
  • Bakkum-Gamez J; Pathology and Laboratory Medicine, University of British Columbia, Vancouver, Canada. dhuntsma@bccancer.bc.ca.
  • McAlpine JN; Gynecology and Obstetrics, Division of Gynecologic Oncology, University of British Columbia, Vancouver, Canada. dhuntsma@bccancer.bc.ca.
  • Anglesio MS; Gynecology and Obstetrics, Mayo Clinic, Rochester, USA. Bakkum.Jamie@mayo.edu.
BMC Cancer ; 15: 415, 2015 May 19.
Article em En | MEDLINE | ID: mdl-25986173
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Ovarianas / Transdução de Sinais / Neoplasias Epiteliais e Glandulares / Adenocarcinoma Mucinoso / Proteínas ras / Mutação Idioma: En Ano de publicação: 2015 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Ovarianas / Transdução de Sinais / Neoplasias Epiteliais e Glandulares / Adenocarcinoma Mucinoso / Proteínas ras / Mutação Idioma: En Ano de publicação: 2015 Tipo de documento: Article