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Major histocompatibility complex associations of ankylosing spondylitis are complex and involve further epistasis with ERAP1.
Cortes, Adrian; Pulit, Sara L; Leo, Paul J; Pointon, Jenny J; Robinson, Philip C; Weisman, Michael H; Ward, Michael; Gensler, Lianne S; Zhou, Xiaodong; Garchon, Henri-Jean; Chiocchia, Gilles; Nossent, Johannes; Lie, Benedicte A; Førre, Øystein; Tuomilehto, Jaakko; Laiho, Kari; Bradbury, Linda A; Elewaut, Dirk; Burgos-Vargas, Ruben; Stebbings, Simon; Appleton, Louise; Farrah, Claire; Lau, Jonathan; Haroon, Nigil; Mulero, Juan; Blanco, Francisco J; Gonzalez-Gay, Miguel A; Lopez-Larrea, C; Bowness, Paul; Gaffney, Karl; Gaston, Hill; Gladman, Dafna D; Rahman, Proton; Maksymowych, Walter P; Crusius, J Bart A; van der Horst-Bruinsma, Irene E; Valle-Oñate, Raphael; Romero-Sánchez, Consuelo; Hansen, Inger Myrnes; Pimentel-Santos, Fernando M; Inman, Robert D; Martin, Javier; Breban, Maxime; Wordsworth, Bryan Paul; Reveille, John D; Evans, David M; de Bakker, Paul I W; Brown, Matthew A.
Afiliação
  • Cortes A; University of Queensland Diamantina Institute, Princess Alexandra Hospital, Brisbane 4102, Australia.
  • Pulit SL; Department of Medical Genetics, Center for Molecular Medicine, University Medical Center Utrecht, Utrecht 3584, The Netherlands.
  • Leo PJ; University of Queensland Diamantina Institute, Princess Alexandra Hospital, Brisbane 4102, Australia.
  • Pointon JJ; NIHR Oxford Musculoskeletal Biomedical Research Unit, Nuffield Orthopaedic Centre, Headington, Oxford OX3 7LD, UK.
  • Robinson PC; University of Queensland Diamantina Institute, Princess Alexandra Hospital, Brisbane 4102, Australia.
  • Weisman MH; Department of Medicine/Rheumatology, Cedars-Sinai Medical Center, Los Angeles, California 90048, USA.
  • Ward M; Intramural Research Program, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, Maryland 20892-1468, USA.
  • Gensler LS; Department of Medicine/Rheumatology, University of California, San Francisco, California 94143, USA.
  • Zhou X; Department of Rheumatology and Clinical Immunogenetics, University of Texas Health Science Center at Houston, Houston, Texas 77030, USA.
  • Garchon HJ; 1] INSERM UMR 1173, Université de Versailles Saint Quentin en Yvelines, Laboratoire d'excellence Inflamex, Saint-Quentn-En-Yvelines 78180, France [2] Genetics Division, Hôpital Ambroise Paré, AP-HP, and Université de Versailles Saint Quentin en Yvelines, Boulogne-Billancourt 78180, France.
  • Chiocchia G; INSERM UMR 1173, Université de Versailles Saint Quentin en Yvelines, Laboratoire d'excellence Inflamex, Saint-Quentn-En-Yvelines 78180, France.
  • Nossent J; 1] School of Medicine, University of Western Australia, Perth, WA 6009, Australia [2] Department of Rheumatology, Sir Charles Gairdner Hospital, Perth, WA 6009, Australia.
  • Lie BA; 1] Department of Medical Genetics, University of Oslo and Oslo University Hospital, Oslo 0310, Norway [2] Department of Immunology, Oslo University Hospital, Oslo 0310, Norway.
  • Førre Ø; Department of Rheumatology, Oslo University Hospital, and University of Oslo, Oslo 0310, Norway.
  • Tuomilehto J; 1] Department of Chronic Disease Prevention, National Institute for Health and Welfare, 00271 Helsinki, Finland [2] Centre for Vascular Prevention, Danube-University Krems, 3500 Krems, Austria [3] Diabetes Research Group, King Abdulaziz University, 21589 Jeddah, Saudi Arabia.
  • Laiho K; Department of Medicine, Paijat-Hame Central Hospital, Lahti, Finland.
  • Bradbury LA; University of Queensland Diamantina Institute, Princess Alexandra Hospital, Brisbane 4102, Australia.
  • Elewaut D; 1] Department of Rheumatology, Gent University Hospital, Gent 9052, Belgium [2] VIB Inflammation Research Center, Ghent University, Gent 9052, Belgium.
  • Burgos-Vargas R; Department of Rheumatology, Hospital General de Mexico and Universidad Nacional Autonoma de Mexico, Mexico City 06726, Mexico.
  • Stebbings S; Department of Medicine, Dunedin School of Medicine, University of Otago, Dunedin 9016, New Zealand.
  • Appleton L; NIHR Oxford Musculoskeletal Biomedical Research Unit, Nuffield Orthopaedic Centre, Headington, Oxford OX3 7LD, UK.
  • Farrah C; NIHR Oxford Musculoskeletal Biomedical Research Unit, Nuffield Orthopaedic Centre, Headington, Oxford OX3 7LD, UK.
  • Lau J; NIHR Oxford Musculoskeletal Biomedical Research Unit, Nuffield Orthopaedic Centre, Headington, Oxford OX3 7LD, UK.
  • Haroon N; Division of Rheumatology, Toronto Western Hospital, University of Toronto, Toronto M5T2S8, Canada.
  • Mulero J; Department of Rheumatology, Hospital Puerta de Hierro, Madrid 28222, Spain.
  • Blanco FJ; Department of Rheumatology, Complejo Hospitalario La Coruña, INIBIC, La Coruña 15006, Spain.
  • Gonzalez-Gay MA; Department of Rheumatology, Hospital Marques de Valcecillas, IFIMAV, Santander 39008, Spain.
  • Lopez-Larrea C; 1] Department of Immunology, Hospital Universitario Central de Asturias, Oviedo 33011, Spain [2] Fundación Renal 'Iñigo Álvarez de Toledo', Madrid 33011, Spain.
  • Bowness P; NIHR Oxford Musculoskeletal Biomedical Research Unit, Nuffield Orthopaedic Centre, Headington, Oxford OX3 7LD, UK.
  • Gaffney K; Department of Rheumatology, Norfolk and Norwich University Hospital, Norwich NR4 7UY, UK.
  • Gaston H; Department of Medicine, University of Cambridge, Addenbrookes Hospital, Cambridge CB2 0SP, UK.
  • Gladman DD; 1] Division of Rheumatology, University of Toronto, Toronto, ON M4N 3M5, Canada [2] Toronto Western Research Institute, Toronto ON M4N 3M5, Canada [3] Psoriatic Arthritis Program, University Health Network, Toronto ON M4N 3M5, Canada.
  • Rahman P; Memorial University of Newfoundland, Newfoundland NL A1B 3X9, Canada.
  • Maksymowych WP; Department of Medicine, University of Alberta, Alberta T6G 2R7, Canada.
  • Crusius JB; Department of Medical Microbiology and Infection Control, Laboratory of Immunogenetics, VU University Medical Center, Amsterdam 1081 BT, The Netherlands.
  • van der Horst-Bruinsma IE; Department of Rheumatology, VU University Medical Centre, Amsterdam 1081 BT, Netherlands.
  • Valle-Oñate R; Spondyloarthropaty Group-Division of Rheumatology, Hospital Militar Central/Universidad de La Sabana, Transversal 3 # 49-00, Bogotá, NA, Colombia.
  • Romero-Sánchez C; Spondyloarthropaty Group-Division of Rheumatology, Hospital Militar Central/Universidad de La Sabana, Transversal 3 # 49-00, Bogotá, NA, Colombia.
  • Hansen IM; Helgelandssykehuset, 8613 Mo i Rana, Norway.
  • Pimentel-Santos FM; Chronic Diseases Research Centre (CEDOC), Faculdade de Ciências Médicas, Universidade Nova de Lisboa, Lisboa 1169-056, Portugal.
  • Inman RD; Division of Rheumatology, Toronto Western Hospital, University of Toronto, Toronto M5T2S8, Canada.
  • Martin J; Instituto de Parasitología y Biomedicina López-Neyra, Consejo Superior de Investigaciones-Científicas, Granada 18100, Spain.
  • Breban M; 1] INSERM UMR 1173, Université de Versailles Saint Quentin en Yvelines, Laboratoire d'excellence Inflamex, Saint-Quentn-En-Yvelines 78180, France [2] Division of Rheumatology, Hôpital Ambroise Paré, AP-HP, and Université de Versailles Saint Quentin en Yvelines, Boulogne-Billancourt 92100, France.
  • Wordsworth BP; NIHR Oxford Musculoskeletal Biomedical Research Unit, Nuffield Orthopaedic Centre, Headington, Oxford OX3 7LD, UK.
  • Reveille JD; Department of Rheumatology and Clinical Immunogenetics, University of Texas Health Science Center at Houston, Houston, Texas 77030, USA.
  • Evans DM; 1] University of Queensland Diamantina Institute, Princess Alexandra Hospital, Brisbane 4102, Australia [2] MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK [3] School of Social and Community Medicine, University of Bristol, Bristol, UK.
  • de Bakker PI; 1] Department of Medical Genetics, Center for Molecular Medicine, University Medical Center Utrecht, Utrecht 3584, The Netherlands [2] Department of Epidemiology, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands.
  • Brown MA; University of Queensland Diamantina Institute, Princess Alexandra Hospital, Brisbane 4102, Australia.
Nat Commun ; 6: 7146, 2015 May 21.
Article em En | MEDLINE | ID: mdl-25994336
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Espondilite Anquilosante / Antígeno HLA-B27 / Antígeno HLA-B40 / Aminopeptidases Idioma: En Ano de publicação: 2015 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Espondilite Anquilosante / Antígeno HLA-B27 / Antígeno HLA-B40 / Aminopeptidases Idioma: En Ano de publicação: 2015 Tipo de documento: Article