Identification of the Adapter Molecule MTSS1 as a Potential Oncogene-Specific Tumor Suppressor in Acute Myeloid Leukemia.

Schemionek, Mirle; Kharabi Masouleh, Behzad; Klaile, Yvonne; Krug, Utz; Hebestreit, Katja; Schubert, Claudia; Dugas, Martin; Büchner, Thomas; Wörmann, Bernhard; Hiddemann, Wolfgang; Berdel, Wolfgang E; Brümmendorf, Tim H; Müller-Tidow, Carsten; Koschmieder, Steffen

Schemionek, Mirle; Kharabi Masouleh, Behzad; Klaile, Yvonne; Krug, Utz; Hebestreit, Katja; Schubert, Claudia; Dugas, Martin; Büchner, Thomas; Wörmann, Bernhard; Hiddemann, Wolfgang; Berdel, Wolfgang E; Brümmendorf, Tim H; Müller-Tidow, Carsten; Koschmieder, Steffen.

Afiliação

Schemionek M; Department of Hematology, Oncology, Hemostaseology, and Stem Cell Transplantation, Faculty of Medicine, RWTH Aachen University, Aachen, Germany.
Kharabi Masouleh B; Department of Hematology, Oncology, Hemostaseology, and Stem Cell Transplantation, Faculty of Medicine, RWTH Aachen University, Aachen, Germany.
Klaile Y; Department of Urology, University of Muenster, Muenster, Germany.
Krug U; Department of Medicine A, Hematology, Oncology, Pneumology, University of Muenster, Muenster, Germany.
Hebestreit K; Institute for Medical Informatics, University of Muenster, Muenster, Germany.
Schubert C; Department of Hematology, Oncology, Hemostaseology, and Stem Cell Transplantation, Faculty of Medicine, RWTH Aachen University, Aachen, Germany.
Dugas M; Institute for Medical Informatics, University of Muenster, Muenster, Germany.
Büchner T; Department of Medicine A, Hematology, Oncology, Pneumology, University of Muenster, Muenster, Germany.
Wörmann B; Membership of the German Society of Hematology and Oncology (DGHO), Berlin, Germany.
Hiddemann W; Department of Internal Medicine III, University of Munich, Munich, Germany; Clinical Cooperation Group Acute Myeloid Leukemia, Helmholtz Zentrum Munich, German Research Center for Environmental Health, Munich, Germany.
Berdel WE; Department of Medicine A, Hematology, Oncology, Pneumology, University of Muenster, Muenster, Germany.
Brümmendorf TH; Department of Hematology, Oncology, Hemostaseology, and Stem Cell Transplantation, Faculty of Medicine, RWTH Aachen University, Aachen, Germany.
Müller-Tidow C; Department of Medicine A, Hematology, Oncology, Pneumology, University of Muenster, Muenster, Germany.
Koschmieder S; Department of Hematology, Oncology, Hemostaseology, and Stem Cell Transplantation, Faculty of Medicine, RWTH Aachen University, Aachen, Germany.

PLoS One ; 10(5): e0125783, 2015.

Article em En | MEDLINE | ID: mdl-25996952

Assuntos

Leucemia Mieloide Aguda/genética; Proteínas dos Microfilamentos/genética; Proteínas de Neoplasias/genética; Linhagem Celular Tumoral; Aberrações Cromossômicas; Análise por Conglomerados; Subunidade alfa 2 de Fator de Ligação ao Core/genética; Expressão Gênica; Perfilação da Expressão Gênica; Regulação Leucêmica da Expressão Gênica/efeitos dos fármacos; Humanos; Cariótipo; Leucemia Mieloide Aguda/metabolismo; Leucemia Mieloide Aguda/mortalidade; Proteínas dos Microfilamentos/metabolismo; Proteínas de Neoplasias/metabolismo; Proteínas de Fusão Oncogênica/genética; Prognóstico; Inibidores de Proteínas Quinases/farmacologia; Proteína 1 Parceira de Translocação de RUNX1; Proteínas Supressoras de Tumor/genética; Proteínas Supressoras de Tumor/metabolismo; Tirosina Quinase 3 Semelhante a fms/genética

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Leucemia Mieloide Aguda / Proteínas dos Microfilamentos / Proteínas de Neoplasias Idioma: En Ano de publicação: 2015 Tipo de documento: Article

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