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The kinase DYRK1A reciprocally regulates the differentiation of Th17 and regulatory T cells.
Khor, Bernard; Gagnon, John D; Goel, Gautam; Roche, Marly I; Conway, Kara L; Tran, Khoa; Aldrich, Leslie N; Sundberg, Thomas B; Paterson, Alison M; Mordecai, Scott; Dombkowski, David; Schirmer, Melanie; Tan, Pauline H; Bhan, Atul K; Roychoudhuri, Rahul; Restifo, Nicholas P; O'Shea, John J; Medoff, Benjamin D; Shamji, Alykhan F; Schreiber, Stuart L; Sharpe, Arlene H; Shaw, Stanley Y; Xavier, Ramnik J.
Afiliação
  • Khor B; Gastrointestinal Unit and Center for the Study of Inflammatory Bowel Disease, Massachusetts General Hospital, Harvard Medical School, Boston, United States.
  • Gagnon JD; Broad Institute of MIT and Harvard, Cambridge, United States.
  • Goel G; Center for Computational and Integrative Biology, Massachusetts General Hospital, Harvard Medical School, Boston, United States.
  • Roche MI; Pulmonary and Critical Care Unit, Massachusetts General Hospital, Boston, United States.
  • Conway KL; Gastrointestinal Unit and Center for the Study of Inflammatory Bowel Disease, Massachusetts General Hospital, Harvard Medical School, Boston, United States.
  • Tran K; Center for Systems Biology, Massachusetts General Hospital, Harvard Medical School, Boston, United States.
  • Aldrich LN; Broad Institute of MIT and Harvard, Cambridge, United States.
  • Sundberg TB; Broad Institute of MIT and Harvard, Cambridge, United States.
  • Paterson AM; Department of Microbiology and Immunobiology, Harvard Medical School, Boston, United States.
  • Mordecai S; Pathology Service, Massachusetts General Hospital, Boston, United States.
  • Dombkowski D; Pathology Service, Massachusetts General Hospital, Boston, United States.
  • Schirmer M; Broad Institute of MIT and Harvard, Cambridge, United States.
  • Tan PH; Center for Systems Biology, Massachusetts General Hospital, Harvard Medical School, Boston, United States.
  • Bhan AK; Pathology Service, Massachusetts General Hospital, Boston, United States.
  • Roychoudhuri R; Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, United States.
  • Restifo NP; Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, United States.
  • O'Shea JJ; Molecular Immunology and Inflammation Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, United States.
  • Medoff BD; Pulmonary and Critical Care Unit, Massachusetts General Hospital, Boston, United States.
  • Shamji AF; Broad Institute of MIT and Harvard, Cambridge, United States.
  • Schreiber SL; Broad Institute of MIT and Harvard, Cambridge, United States.
  • Sharpe AH; Department of Microbiology and Immunobiology, Harvard Medical School, Boston, United States.
  • Shaw SY; Center for Systems Biology, Massachusetts General Hospital, Harvard Medical School, Boston, United States.
  • Xavier RJ; Gastrointestinal Unit and Center for the Study of Inflammatory Bowel Disease, Massachusetts General Hospital, Harvard Medical School, Boston, United States.
Elife ; 42015 May 22.
Article em En | MEDLINE | ID: mdl-25998054

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas Tirosina Quinases / Diferenciação Celular / Proteínas Serina-Treonina Quinases / Linfócitos T Reguladores / Células Th17 / Homeostase Idioma: En Ano de publicação: 2015 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas Tirosina Quinases / Diferenciação Celular / Proteínas Serina-Treonina Quinases / Linfócitos T Reguladores / Células Th17 / Homeostase Idioma: En Ano de publicação: 2015 Tipo de documento: Article