Real-time single-molecule studies of the motions of DNA polymerase fingers illuminate DNA synthesis mechanisms.

Evans, Geraint W; Hohlbein, Johannes; Craggs, Timothy; Aigrain, Louise; Kapanidis, Achillefs N

Evans, Geraint W; Hohlbein, Johannes; Craggs, Timothy; Aigrain, Louise; Kapanidis, Achillefs N.

Afiliação

Evans GW; Department of Physics and Biological Physics Research Group, Clarendon Laboratory, University of Oxford, Parks Road, Oxford OX1 3PU, United Kingdom.
Hohlbein J; Department of Physics and Biological Physics Research Group, Clarendon Laboratory, University of Oxford, Parks Road, Oxford OX1 3PU, United Kingdom.
Craggs T; Department of Physics and Biological Physics Research Group, Clarendon Laboratory, University of Oxford, Parks Road, Oxford OX1 3PU, United Kingdom.
Aigrain L; Department of Physics and Biological Physics Research Group, Clarendon Laboratory, University of Oxford, Parks Road, Oxford OX1 3PU, United Kingdom.
Kapanidis AN; Department of Physics and Biological Physics Research Group, Clarendon Laboratory, University of Oxford, Parks Road, Oxford OX1 3PU, United Kingdom a.kapanidis1@physics.ox.ac.uk.

Nucleic Acids Res ; 43(12): 5998-6008, 2015 Jul 13.

Article em En | MEDLINE | ID: mdl-26013816

Assuntos

DNA Polimerase Dirigida por DNA/química; DNA/biossíntese; DNA/química; DNA Polimerase Dirigida por DNA/metabolismo; Desoxirribonucleotídeos/metabolismo; Transferência Ressonante de Energia de Fluorescência; Cinética; Movimento (Física); Conformação Proteica

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: DNA / DNA Polimerase Dirigida por DNA Idioma: En Ano de publicação: 2015 Tipo de documento: Article

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: DNA / DNA Polimerase Dirigida por DNA Idioma: En Ano de publicação: 2015 Tipo de documento: Article