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Causal Modeling of Cancer-Stromal Communication Identifies PAPPA as a Novel Stroma-Secreted Factor Activating NFκB Signaling in Hepatocellular Carcinoma.
Engelmann, Julia C; Amann, Thomas; Ott-Rötzer, Birgitta; Nützel, Margit; Reinders, Yvonne; Reinders, Jörg; Thasler, Wolfgang E; Kristl, Theresa; Teufel, Andreas; Huber, Christian G; Oefner, Peter J; Spang, Rainer; Hellerbrand, Claus.
Afiliação
  • Engelmann JC; Department of Statistical Bioinformatics, University of Regensburg, Regensburg, Germany.
  • Amann T; Department of Internal Medicine I, University Hospital Regensburg, Regensburg, Germany.
  • Ott-Rötzer B; Department of Internal Medicine I, University Hospital Regensburg, Regensburg, Germany.
  • Nützel M; Department of Internal Medicine I, University Hospital Regensburg, Regensburg, Germany.
  • Reinders Y; Institute of Functional Genomics, University of Regensburg, Regensburg, Germany.
  • Reinders J; Institute of Functional Genomics, University of Regensburg, Regensburg, Germany.
  • Thasler WE; Biobank under the authority of Human Tissue and Cell Research (HTCR) and Center for Liver Cell Research, Department of General, Visceral, Transplantation, Vascular and Thoracic Surgery, Hospital of Ludwig-Maximilians-University of Munich, Munich, Germany.
  • Kristl T; Department of Molecular Biology, Division of Chemistry and Bioanalytics, University of Salzburg, Salzburg, Austria.
  • Teufel A; Department of Internal Medicine I, University Hospital Regensburg, Regensburg, Germany.
  • Huber CG; Department of Molecular Biology, Division of Chemistry and Bioanalytics, University of Salzburg, Salzburg, Austria.
  • Oefner PJ; Institute of Functional Genomics, University of Regensburg, Regensburg, Germany.
  • Spang R; Department of Statistical Bioinformatics, University of Regensburg, Regensburg, Germany.
  • Hellerbrand C; Department of Internal Medicine I, University Hospital Regensburg, Regensburg, Germany.
PLoS Comput Biol ; 11(5): e1004293, 2015 May.
Article em En | MEDLINE | ID: mdl-26020769
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteína Plasmática A Associada à Gravidez / NF-kappa B / Carcinoma Hepatocelular / Neoplasias Hepáticas Idioma: En Ano de publicação: 2015 Tipo de documento: Article
Texto completo
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XML
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteína Plasmática A Associada à Gravidez / NF-kappa B / Carcinoma Hepatocelular / Neoplasias Hepáticas Idioma: En Ano de publicação: 2015 Tipo de documento: Article