[Panton-Valentine leukocidin-positive osteoarticular infections]. / Infections ostéoarticulaires à Staphylococcus aureus portant le gène de la leucocidine de Panton-Valentine.
Med Sante Trop
; 25(2): 184-8, 2015.
Article
em Fr
| MEDLINE
| ID: mdl-26039246
ABSTRACT
OBJECTIVES:
The aim of our study was to evaluate the frequency of osteoarticular infections with Panton-Valentine leukocidin-positive (PVL) Staphylococcus aureus (PVL-SA) among patients admitted to the orthopedic ward at the Sahloul University Hospital (Sousse, Tunisia) and to study the characteristics of these strains and patients. MATERIALS ANDMETHODS:
We conducted a retrospective descriptive study over a 5-year period. Bacterial identification, antibiotic susceptibility, and molecular study (PCR to detect of the luk-PV gene that encodes PVL) were performed for 44 S. aureus isolates.RESULTS:
Panton-Valentine toxin was found in 41% of S. aureus cases, mainly males, and 39% of the PVL(+) cases were methicillin-sensitive (MSSA). These strains constitute a reservoir of PVL genes that can lead to the emergence and spread of PVL-SA clones resistant to methicillin (MRSA). In our series, PVL-MRSA accounted for 9% of all S. aureus isolates. Their profile and antibiotic resistance is that of clone ST80, frequently isolated in Europe and also reported in Algeria and Tunisia.CONCLUSION:
It is desirable to test for PVL routinely in the laboratory to implement appropriate treatment and to monitor the epidemiology of these PVL-SA strains actively. Further measures should be undertaken to prevent and fight infections by these strains.Palavras-chave
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Base de dados:
MEDLINE
Assunto principal:
Infecções Estafilocócicas
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Toxinas Bacterianas
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Doenças Ósseas Infecciosas
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Exotoxinas
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Artropatias
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Leucocidinas
Idioma:
Fr
Ano de publicação:
2015
Tipo de documento:
Article