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Synthesis and structure-activity relationship of aminoarylthiazole derivatives as correctors of the chloride transport defect in cystic fibrosis.
Pesce, Emanuela; Bellotti, Marta; Liessi, Nara; Guariento, Sara; Damonte, Gianluca; Cichero, Elena; Galatini, Andrea; Salis, Annalisa; Gianotti, Ambra; Pedemonte, Nicoletta; Zegarra-Moran, Olga; Fossa, Paola; Galietta, Luis J V; Millo, Enrico.
Afiliação
  • Pesce E; Istituto Giannina Gaslini, via Gerolamo Gaslini 5, 16147 Genoa, Italy.
  • Bellotti M; Department of Experimental Medicine, Section of Biochemistry, University of Genoa, Viale Benedetto XV 1, 16132 Genoa, Italy; Center of Excellence for Biomedical Research (CEBR), University of Genoa, Viale Benedetto XV 5, 16132 Genoa, Italy.
  • Liessi N; Department of Experimental Medicine, Section of Biochemistry, University of Genoa, Viale Benedetto XV 1, 16132 Genoa, Italy.
  • Guariento S; Department of Pharmacy, Section of Medicinal Chemistry, School of Medical and Pharmaceutical Sciences, University of Genoa, Viale Benedetto XV, 3, 16132 Genoa, Italy.
  • Damonte G; Department of Experimental Medicine, Section of Biochemistry, University of Genoa, Viale Benedetto XV 1, 16132 Genoa, Italy; Center of Excellence for Biomedical Research (CEBR), University of Genoa, Viale Benedetto XV 5, 16132 Genoa, Italy.
  • Cichero E; Department of Pharmacy, Section of Medicinal Chemistry, School of Medical and Pharmaceutical Sciences, University of Genoa, Viale Benedetto XV, 3, 16132 Genoa, Italy.
  • Galatini A; Department of Chemistry and Industrial Chemistry, University of Genoa, Via Dodecaneso 31, 16146 Genoa, Italy.
  • Salis A; Center of Excellence for Biomedical Research (CEBR), University of Genoa, Viale Benedetto XV 5, 16132 Genoa, Italy.
  • Gianotti A; Istituto Giannina Gaslini, via Gerolamo Gaslini 5, 16147 Genoa, Italy.
  • Pedemonte N; Istituto Giannina Gaslini, via Gerolamo Gaslini 5, 16147 Genoa, Italy.
  • Zegarra-Moran O; Istituto Giannina Gaslini, via Gerolamo Gaslini 5, 16147 Genoa, Italy.
  • Fossa P; Department of Pharmacy, Section of Medicinal Chemistry, School of Medical and Pharmaceutical Sciences, University of Genoa, Viale Benedetto XV, 3, 16132 Genoa, Italy.
  • Galietta LJ; Istituto Giannina Gaslini, via Gerolamo Gaslini 5, 16147 Genoa, Italy.
  • Millo E; Department of Experimental Medicine, Section of Biochemistry, University of Genoa, Viale Benedetto XV 1, 16132 Genoa, Italy; Center of Excellence for Biomedical Research (CEBR), University of Genoa, Viale Benedetto XV 5, 16132 Genoa, Italy. Electronic address: enrico.millo@unige.it.
Eur J Med Chem ; 99: 14-35, 2015 Jun 24.
Article em En | MEDLINE | ID: mdl-26041577
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Tiazóis / Desenho de Fármacos / Cloretos / Fibrose Cística Idioma: En Ano de publicação: 2015 Tipo de documento: Article
Texto completo
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XML
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Tiazóis / Desenho de Fármacos / Cloretos / Fibrose Cística Idioma: En Ano de publicação: 2015 Tipo de documento: Article