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Targeted Inhibition of Phosphoinositide 3-Kinase/Mammalian Target of Rapamycin Sensitizes Pancreatic Cancer Cells to Doxorubicin without Exacerbating Cardiac Toxicity.
Durrant, David E; Das, Anindita; Dyer, Samya; Tavallai, Seyedmehrad; Dent, Paul; Kukreja, Rakesh C.
Afiliação
  • Durrant DE; Department of Biochemistry and Molecular Biology (D.E.D., S.T., P.D.), Department of Internal Medicine, Division of Cardiology, Pauley Heart Center (A.D., S.D., R.C.K.), and Department of Physiology and Biophysics (R.C.K.), Virginia Commonwealth University Medical Center, Richmond, Virginia.
  • Das A; Department of Biochemistry and Molecular Biology (D.E.D., S.T., P.D.), Department of Internal Medicine, Division of Cardiology, Pauley Heart Center (A.D., S.D., R.C.K.), and Department of Physiology and Biophysics (R.C.K.), Virginia Commonwealth University Medical Center, Richmond, Virginia.
  • Dyer S; Department of Biochemistry and Molecular Biology (D.E.D., S.T., P.D.), Department of Internal Medicine, Division of Cardiology, Pauley Heart Center (A.D., S.D., R.C.K.), and Department of Physiology and Biophysics (R.C.K.), Virginia Commonwealth University Medical Center, Richmond, Virginia.
  • Tavallai S; Department of Biochemistry and Molecular Biology (D.E.D., S.T., P.D.), Department of Internal Medicine, Division of Cardiology, Pauley Heart Center (A.D., S.D., R.C.K.), and Department of Physiology and Biophysics (R.C.K.), Virginia Commonwealth University Medical Center, Richmond, Virginia.
  • Dent P; Department of Biochemistry and Molecular Biology (D.E.D., S.T., P.D.), Department of Internal Medicine, Division of Cardiology, Pauley Heart Center (A.D., S.D., R.C.K.), and Department of Physiology and Biophysics (R.C.K.), Virginia Commonwealth University Medical Center, Richmond, Virginia.
  • Kukreja RC; Department of Biochemistry and Molecular Biology (D.E.D., S.T., P.D.), Department of Internal Medicine, Division of Cardiology, Pauley Heart Center (A.D., S.D., R.C.K.), and Department of Physiology and Biophysics (R.C.K.), Virginia Commonwealth University Medical Center, Richmond, Virginia rakesh@v
Mol Pharmacol ; 88(3): 512-23, 2015 Sep.
Article em En | MEDLINE | ID: mdl-26101222
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Pancreáticas / Quinolinas / Doxorrubicina / Inibidores de Proteínas Quinases / Serina-Treonina Quinases TOR / Inibidores de Fosfoinositídeo-3 Quinase / Imidazóis / Antibióticos Antineoplásicos Idioma: En Ano de publicação: 2015 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Pancreáticas / Quinolinas / Doxorrubicina / Inibidores de Proteínas Quinases / Serina-Treonina Quinases TOR / Inibidores de Fosfoinositídeo-3 Quinase / Imidazóis / Antibióticos Antineoplásicos Idioma: En Ano de publicação: 2015 Tipo de documento: Article