Onset Time and Durability of Huntingtin Suppression in Rhesus Putamen After Direct Infusion of Antihuntingtin siRNA.

Grondin, Richard; Ge, Pei; Chen, Qingmin; Sutherland, Jessica E; Zhang, Zhiming; Gash, Don M; Stiles, David K; Stewart, Gregory R; Sah, Dinah W Y; Kaemmerer, William F

Grondin, Richard; Ge, Pei; Chen, Qingmin; Sutherland, Jessica E; Zhang, Zhiming; Gash, Don M; Stiles, David K; Stewart, Gregory R; Sah, Dinah W Y; Kaemmerer, William F.

Afiliação

Grondin R; Department of Anatomy and Neurobiology, University of Kentucky College of Medicine, Lexington, Kentucky, USA.
Ge P; Alnylam Pharmaceuticals, Cambridge, Massachusetts, USA.
Chen Q; Alnylam Pharmaceuticals, Cambridge, Massachusetts, USA.
Sutherland JE; Alnylam Pharmaceuticals, Cambridge, Massachusetts, USA.
Zhang Z; Department of Anatomy and Neurobiology, University of Kentucky College of Medicine, Lexington, Kentucky, USA.
Gash DM; Department of Anatomy and Neurobiology, University of Kentucky College of Medicine, Lexington, Kentucky, USA.
Stiles DK; Drug Delivery R&D, Neuromodulation, Medtronic Inc., Minneapolis, Minnesota, USA.
Stewart GR; Drug Delivery R&D, Neuromodulation, Medtronic Inc., Minneapolis, Minnesota, USA.
Sah DW; Alnylam Pharmaceuticals, Cambridge, Massachusetts, USA.
Kaemmerer WF; Drug Delivery R&D, Neuromodulation, Medtronic Inc., Minneapolis, Minnesota, USA.

Mol Ther Nucleic Acids ; 4: e245, 2015 Jun 30.

Article em En | MEDLINE | ID: mdl-26125484

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Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2015 Tipo de documento: Article

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Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2015 Tipo de documento: Article