Dissecting the Role of Smooth Muscle Cells versus Pericytes in Regulating Cerebral Blood Flow Using In Vivo Optical Imaging.

Mazzoni, Jenna; Cutforth, Tyler; Agalliu, Dritan

Dissecting the Role of Smooth Muscle Cells versus Pericytes in Regulating Cerebral Blood Flow Using In Vivo Optical Imaging.

Mazzoni, Jenna; Cutforth, Tyler; Agalliu, Dritan.

Afiliação

Mazzoni J; Department of Developmental and Cell Biology, University of California, Irvine, Irvine, CA 92697, USA.
Cutforth T; Departments of Neurology and Pathology & Cell Biology, Columbia University Medical Center, New York, NY 10032, USA.
Agalliu D; Department of Developmental and Cell Biology, University of California, Irvine, Irvine, CA 92697, USA; Departments of Neurology and Pathology & Cell Biology, Columbia University Medical Center, New York, NY 10032, USA. Electronic address: da191@cumc.columbia.edu.

Neuron ; 87(1): 4-6, 2015 Jul 01.

Article em En | MEDLINE | ID: mdl-26139364

ABSTRACT

ABSTRACT

The brain regulates blood flow to match energy demand to nutrient supply. In this issue of Neuron, using in vivo optical imaging and optogenetics, Hill et al. (2015) report that arteriolar smooth muscle cells are key players in regulating cerebral blood flow in the healthy state and contribute to the "no reflow" phenomenon after ischemic stroke.

Assuntos

Isquemia Encefálica; Córtex Cerebral/irrigação sanguínea; Circulação Cerebrovascular/fisiologia; Contração Muscular/fisiologia; Miócitos de Músculo Liso/fisiologia; Pericitos/fisiologia; Animais; Humanos

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Córtex Cerebral / Isquemia Encefálica / Circulação Cerebrovascular / Pericitos / Miócitos de Músculo Liso / Contração Muscular Idioma: En Ano de publicação: 2015 Tipo de documento: Article

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