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Potent and Selective Triazole-Based Inhibitors of the Hypoxia-Inducible Factor Prolyl-Hydroxylases with Activity in the Murine Brain.
Chan, Mun Chiang; Atasoylu, Onur; Hodson, Emma; Tumber, Anthony; Leung, Ivanhoe K H; Chowdhury, Rasheduzzaman; Gómez-Pérez, Verónica; Demetriades, Marina; Rydzik, Anna M; Holt-Martyn, James; Tian, Ya-Min; Bishop, Tammie; Claridge, Timothy D W; Kawamura, Akane; Pugh, Christopher W; Ratcliffe, Peter J; Schofield, Christopher J.
Afiliação
  • Chan MC; Chemistry Research Laboratory, Department of Chemistry, University of Oxford, Oxford, United Kingdom; Centre for Cellular and Molecular Physiology, University of Oxford, Oxford, United Kingdom.
  • Atasoylu O; Chemistry Research Laboratory, Department of Chemistry, University of Oxford, Oxford, United Kingdom.
  • Hodson E; Centre for Cellular and Molecular Physiology, University of Oxford, Oxford, United Kingdom.
  • Tumber A; Target Discovery Institute, University of Oxford, Oxford, United Kingdom.
  • Leung IK; Chemistry Research Laboratory, Department of Chemistry, University of Oxford, Oxford, United Kingdom.
  • Chowdhury R; Chemistry Research Laboratory, Department of Chemistry, University of Oxford, Oxford, United Kingdom.
  • Gómez-Pérez V; Chemistry Research Laboratory, Department of Chemistry, University of Oxford, Oxford, United Kingdom.
  • Demetriades M; Chemistry Research Laboratory, Department of Chemistry, University of Oxford, Oxford, United Kingdom.
  • Rydzik AM; Chemistry Research Laboratory, Department of Chemistry, University of Oxford, Oxford, United Kingdom.
  • Holt-Martyn J; Chemistry Research Laboratory, Department of Chemistry, University of Oxford, Oxford, United Kingdom.
  • Tian YM; Centre for Cellular and Molecular Physiology, University of Oxford, Oxford, United Kingdom.
  • Bishop T; Centre for Cellular and Molecular Physiology, University of Oxford, Oxford, United Kingdom.
  • Claridge TD; Chemistry Research Laboratory, Department of Chemistry, University of Oxford, Oxford, United Kingdom.
  • Kawamura A; Chemistry Research Laboratory, Department of Chemistry, University of Oxford, Oxford, United Kingdom.
  • Pugh CW; Centre for Cellular and Molecular Physiology, University of Oxford, Oxford, United Kingdom.
  • Ratcliffe PJ; Centre for Cellular and Molecular Physiology, University of Oxford, Oxford, United Kingdom.
  • Schofield CJ; Chemistry Research Laboratory, Department of Chemistry, University of Oxford, Oxford, United Kingdom.
PLoS One ; 10(7): e0132004, 2015.
Article em En | MEDLINE | ID: mdl-26147748
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Triazóis / Encéfalo / Acidente Vascular Cerebral / Inibidores Enzimáticos / Prolina Dioxigenases do Fator Induzível por Hipóxia Idioma: En Ano de publicação: 2015 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Triazóis / Encéfalo / Acidente Vascular Cerebral / Inibidores Enzimáticos / Prolina Dioxigenases do Fator Induzível por Hipóxia Idioma: En Ano de publicação: 2015 Tipo de documento: Article