The relationship between the prevalence of Helicobacter pylori and serum levels of vitamin B12 in women 10-49 years.

ABSTRACT

AIM: The aim of this study was to determine the relationship between serum vitamin B12 and Helicobacter(H.) pylori prevalence in women between 10-49 years. METHODS: This cross-sectional (descriptive and analytical) study was conducted in the city of Samirom located in Isfahan, Iran in 2013. The population studied consisted of 100 women between 10-49 years and they were selected by convenience sampling. Data collection tools was checklist in which its content validity and reliability were confirmed. The data were entered into SPSS 16 software and were analyzed using descriptive statistics methods and univariate and multivariate inferential statistics methods. RESULTS: The mean age of the study population was 29.5 ± 1.04. Also 29% of the population studied was infected with H. pylori, and prevalence of serum vitamin B12 less than 160 was 47%. After adjusted the effect of confounder variables with multivariate logistic regression analysis, the odds of infected with H. pylori in peoples with vitamin B12 less than 160, was 4.8 times the peoples with vitamin B12 normal (Equal and greater than 160) that this different was statistically significant (P<0.001). CONCLUSION: The results showed that serum levels of vitamin B12 is a determinant factor in the prevalence of H. pylori.