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Discovery of a BTK/MNK dual inhibitor for lymphoma and leukemia.
Wu, H; Hu, C; Wang, A; Weisberg, E L; Chen, Y; Yun, C-H; Wang, W; Liu, Y; Liu, X; Tian, B; Wang, J; Zhao, Z; Liang, Y; Li, B; Wang, L; Wang, B; Chen, C; Buhrlage, S J; Qi, Z; Zou, F; Nonami, A; Li, Y; Fernandes, S M; Adamia, S; Stone, R M; Galinsky, I A; Wang, X; Yang, G; Griffin, J D; Brown, J R; Eck, M J; Liu, J; Gray, N S; Liu, Q.
Afiliação
  • Wu H; High Magnetic Field laboratory, Chinese Academy of Sciences, Hefei, Anhui, China.
  • Hu C; University of Science and Technology of China, Anhui, Hefei, P. R. China.
  • Wang A; High Magnetic Field laboratory, Chinese Academy of Sciences, Hefei, Anhui, China.
  • Weisberg EL; High Magnetic Field laboratory, Chinese Academy of Sciences, Hefei, Anhui, China.
  • Chen Y; University of Science and Technology of China, Anhui, Hefei, P. R. China.
  • Yun CH; Department of Medical Oncology, Dana Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.
  • Wang W; High Magnetic Field laboratory, Chinese Academy of Sciences, Hefei, Anhui, China.
  • Liu Y; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, USA.
  • Liu X; High Magnetic Field laboratory, Chinese Academy of Sciences, Hefei, Anhui, China.
  • Tian B; Department of Medical Oncology, Dana Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.
  • Wang J; High Magnetic Field laboratory, Chinese Academy of Sciences, Hefei, Anhui, China.
  • Zhao Z; University of Science and Technology of China, Anhui, Hefei, P. R. China.
  • Liang Y; Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology and Visual Science Key Laboratory, Beijing, China.
  • Li B; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, USA.
  • Wang L; High Magnetic Field laboratory, Chinese Academy of Sciences, Hefei, Anhui, China.
  • Wang B; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, USA.
  • Chen C; High Magnetic Field laboratory, Chinese Academy of Sciences, Hefei, Anhui, China.
  • Buhrlage SJ; High Magnetic Field laboratory, Chinese Academy of Sciences, Hefei, Anhui, China.
  • Qi Z; High Magnetic Field laboratory, Chinese Academy of Sciences, Hefei, Anhui, China.
  • Zou F; High Magnetic Field laboratory, Chinese Academy of Sciences, Hefei, Anhui, China.
  • Nonami A; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, USA.
  • Li Y; High Magnetic Field laboratory, Chinese Academy of Sciences, Hefei, Anhui, China.
  • Fernandes SM; High Magnetic Field laboratory, Chinese Academy of Sciences, Hefei, Anhui, China.
  • Adamia S; Department of Medical Oncology, Dana Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.
  • Stone RM; Department of Medical Oncology, Dana Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.
  • Galinsky IA; Department of Medical Oncology, Dana Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.
  • Wang X; Department of Medical Oncology, Dana Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.
  • Yang G; Department of Medical Oncology, Dana Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.
  • Griffin JD; Department of Medical Oncology, Dana Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.
  • Brown JR; Department of Lymphoma, Sino-US Center for Lymphoma and Leukemia, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center of Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin, China.
  • Eck MJ; Department of Medical Oncology, Dana Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.
  • Liu J; Department of Medical Oncology, Dana Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.
  • Gray NS; Department of Medical Oncology, Dana Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.
  • Liu Q; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, USA.
Leukemia ; 30(1): 173-81, 2016 Jan.
Article em En | MEDLINE | ID: mdl-26165234
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas Tirosina Quinases / Leucemia / Proteínas Serina-Treonina Quinases / Peptídeos e Proteínas de Sinalização Intracelular / Inibidores de Proteínas Quinases / Linfoma Idioma: En Ano de publicação: 2016 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas Tirosina Quinases / Leucemia / Proteínas Serina-Treonina Quinases / Peptídeos e Proteínas de Sinalização Intracelular / Inibidores de Proteínas Quinases / Linfoma Idioma: En Ano de publicação: 2016 Tipo de documento: Article