Simultaneous PET/MRI in stroke: a case series.
J Cereb Blood Flow Metab
; 35(9): 1421-5, 2015 Sep.
Article
em En
| MEDLINE
| ID: mdl-26174332
ABSTRACT
Prospective studies on magnetic resonance imaging (MRI)-guided systemic thrombolysis >4.5 hours after stroke onset did not reach their primary end points. It was discussed and observed in post hoc data re-assessment that this was partly because of limited MRI accuracy to measure critical hypoperfusion. We report the first cases of simultaneous [(15)O]H2O-positron emission tomography (PET)/MRI in stroke patients and an ovine model. Discrepancies between simultaneously obtained PET and MRI readouts were observed that might explain the above current limitations of stroke MRI. By offering highly complementary information, [(15)O]H2O-PET/MRI might help to identify critically hypoperfused tissue resulting in an improved patient stratification in thrombolysis trials.
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Base de dados:
MEDLINE
Assunto principal:
Encéfalo
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Imageamento por Ressonância Magnética
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Acidente Vascular Cerebral
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Tomografia por Emissão de Pósitrons
Idioma:
En
Ano de publicação:
2015
Tipo de documento:
Article