A New Turn on Fluorescent Probe for Selective Detection of Cysteine/Homocysteine.
J Fluoresc
; 25(5): 1315-21, 2015 Sep.
Article
em En
| MEDLINE
| ID: mdl-26179077
ABSTRACT
A new fluorescent probe (probe 1) was developed for recognition of cysteine (Cys) and homocysteine (Hcy). Probe 1 exhibited a large absorption peak blue-shift (107 nm) as well as enhanced fluorescence responses to Cys/Hcy based on cyclization of thiol containing amino acids with aldehydes, inhibiting the C = N isomerization-induced quenching process by an intramolecular hydrogen bond. The detection mechanism was proved by (1)H NMR and mass spectrometry analysis.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Cisteína
/
Corantes Fluorescentes
/
Homocisteína
Idioma:
En
Ano de publicação:
2015
Tipo de documento:
Article