Leukostasis Retinopathy: A New Clinical Manifestation of Chronic Myeloid Leukemia With Severe Hyperleukocytosis.
Ophthalmic Surg Lasers Imaging Retina
; 46(7): 768-70, 2015.
Article
em En
| MEDLINE
| ID: mdl-26247460
ABSTRACT
The authors report a new clinical manifestation of chronic myeloid leukemia. A 41-year-old man presented with significant visual loss, leading to a diagnosis of chronic myeloid leukemia. His white blood count exceeded that of any previously reported case of the disease with documented retinal findings (562,000/mm(3)), and clinical evaluation revealed the blockage of temporal retinal vessels by white blood cells. Hematologic findings resolved within 1 month of chemotherapy with dasatinib, and further treatment with intravitreal anti-VEGF agents resulted in the complete resolution of fundus findings. The authors propose that leukostasis retinopathy be recognized as a clinical manifestation of this life-threatening disease.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Doenças Retinianas
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Leucemia Mielogênica Crônica BCR-ABL Positiva
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Leucostasia
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Leucocitose
Idioma:
En
Ano de publicação:
2015
Tipo de documento:
Article