Early events induced by the toxin deoxynivalenol lead to programmed cell death in Nicotiana tabacum cells.
Plant Sci
; 238: 148-57, 2015 Sep.
Article
em En
| MEDLINE
| ID: mdl-26259183
ABSTRACT
Deoxynivalenol (DON) is a mycotoxin affecting animals and plants. This toxin synthesized by Fusarium culmorum and Fusarium graminearum is currently believed to play a decisive role in the fungal phytopathogenesis as a virulence factor. Using cultured cells of Nicotiana tabacum BY2, we showed that DON-induced programmed cell death (PCD) could require transcription and translation processes, in contrast to what was observed in animal cells. DON could induce different cross-linked pathways involving (i) reactive oxygen species (ROS) generation linked, at least partly, to a mitochondrial dysfunction and a transcriptional down-regulation of the alternative oxidase (Aox1) gene and (ii) regulation of ion channel activities participating in cell shrinkage, to achieve PCD.
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MEDLINE
Assunto principal:
Nicotiana
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Tricotecenos
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Apoptose
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Células Vegetais
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Micotoxinas
Idioma:
En
Ano de publicação:
2015
Tipo de documento:
Article