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GenomeLaser: fast and accurate haplotyping from pedigree genotypes.
Li, Wenzhi; Fu, Guoxing; Rao, Weinian; Xu, Wei; Ma, Li; Guo, Shiwen; Song, Qing.
Afiliação
  • Li W; Department of Neurosurgery, First Affiliated Hospital of Medical School, Xi'an Jiaotong University, Xi'an, Shaanxi, 710061 China, Cardiovascular Research Institute and Department of Medicine, Morehouse School of Medicine, Atlanta, GA, 30310 USA.
  • Fu G; 4DGENOME Inc, Atlanta, GA, 30033 USA and.
  • Rao W; 4DGENOME Inc, Atlanta, GA, 30033 USA and.
  • Xu W; Cardiovascular Research Institute and Department of Medicine, Morehouse School of Medicine, Atlanta, GA, 30310 USA.
  • Ma L; Cardiovascular Research Institute and Department of Medicine, Morehouse School of Medicine, Atlanta, GA, 30310 USA, 4DGENOME Inc, Atlanta, GA, 30033 USA and.
  • Guo S; Department of Neurosurgery, First Affiliated Hospital of Medical School, Xi'an Jiaotong University, Xi'an, Shaanxi, 710061 China.
  • Song Q; Cardiovascular Research Institute and Department of Medicine, Morehouse School of Medicine, Atlanta, GA, 30310 USA, 4DGENOME Inc, Atlanta, GA, 30033 USA and Center of Big Data and Bioinformatics, First Affiliated Hospital of Medical School, Xi'an Jiaotong University, Xi'an, Shaanxi, 710061 China.
Bioinformatics ; 31(24): 3984-7, 2015 Dec 15.
Article em En | MEDLINE | ID: mdl-26286810
ABSTRACT
UNLABELLED We present a software tool called GenomeLaser that determines the haplotypes of each person from unphased high-throughput genotypes in family pedigrees. This method features high accuracy, chromosome-range phasing distance, linear computing, flexible pedigree types and flexible genetic marker types. AVAILABILITY AND IMPLEMENTATION http//www.4dgenome.com/software/genomelaser.html.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Linhagem / Haplótipos / Software / Técnicas de Genotipagem Idioma: En Ano de publicação: 2015 Tipo de documento: Article
Texto completo
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PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Linhagem / Haplótipos / Software / Técnicas de Genotipagem Idioma: En Ano de publicação: 2015 Tipo de documento: Article