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Molecular knots in biology and chemistry.
Lim, Nicole C H; Jackson, Sophie E.
Afiliação
  • Lim NC; Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, UK. Faculty of Sciences, Universiti Brunei Darussalam, Gadong BE 1410, Brunei Darussalam.
J Phys Condens Matter ; 27(35): 354101, 2015 Sep 09.
Article em En | MEDLINE | ID: mdl-26291690
Knots and entanglements are ubiquitous. Beyond their aesthetic appeal, these fascinating topological entities can be either useful or cumbersome. In recent decades, the importance and prevalence of molecular knots have been increasingly recognised by scientists from different disciplines. In this review, we provide an overview on the various molecular knots found in naturally occurring biological systems (DNA, RNA and proteins), and those created by synthetic chemists. We discuss the current knowledge in these fields, including recent developments in experimental and, in some cases, computational studies which are beginning to shed light into the complex interplay between the structure, formation and properties of these topologically intricate molecules.
Assuntos

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Materiais Biocompatíveis / Biofísica / Substâncias Macromoleculares Idioma: En Ano de publicação: 2015 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Materiais Biocompatíveis / Biofísica / Substâncias Macromoleculares Idioma: En Ano de publicação: 2015 Tipo de documento: Article