Selective Expression of Galanin in Neuronal-Like Cells of the Human Carotid Body.
Adv Exp Med Biol
; 860: 315-23, 2015.
Article
em En
| MEDLINE
| ID: mdl-26303496
ABSTRACT
The carotid body is a neural-crest-derived organ devoted to respiratory homeostasis through sensing changes in blood oxygen levels. The sensory units are the glomeruli composed of clusters of neuronal-like (type I) cells surrounded by glial-like (type II) cells. During chronic hypoxia, the carotid body shows growth, with increasing neuronal-like cell numbers. We are interested in the signals involved in the mechanisms that underlie such response, because they are not well understood and described. Considering that, in literature, galanin is involved in neurotrophic or neuroprotective role in cell proliferation and is expressed in animal carotid body, we investigated its expression in human. Here, we have shown the expression and localisation of galanin in the human carotid body.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Corpo Carotídeo
/
Galanina
/
Neurônios
Idioma:
En
Ano de publicação:
2015
Tipo de documento:
Article