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Rapid prediction of inducible clarithromycin resistance in Mycobacterium abscessus.
Zhu, Yan Chun; Mitchell, Kara K; Nazarian, Elizabeth J; Escuyer, Vincent E; Musser, Kimberlee A.
Afiliação
  • Zhu YC; Wadsworth Center, New York State Department of Health, Albany, NY, USA.
  • Mitchell KK; Wadsworth Center, New York State Department of Health, Albany, NY, USA.
  • Nazarian EJ; Wadsworth Center, New York State Department of Health, Albany, NY, USA.
  • Escuyer VE; Wadsworth Center, New York State Department of Health, Albany, NY, USA.
  • Musser KA; Wadsworth Center, New York State Department of Health, Albany, NY, USA. Electronic address: kimberlee.musser@health.ny.gov.
Mol Cell Probes ; 29(6): 514-516, 2015 Dec.
Article em En | MEDLINE | ID: mdl-26334290
We have developed a single tube TaqMan(®) real-time PCR assay that differentiates the full-length and truncated erm(41) gene to predict inducible resistance to clarithromycin in Mycobacterium abscessus. A study of 87 clinical isolates found this assay to be 90.8% concordant to conventional drug susceptibility testing results for the prediction of inducible clarithromycin drug resistance.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas de Bactérias / Reação em Cadeia da Polimerase em Tempo Real / Micobactérias não Tuberculosas Idioma: En Ano de publicação: 2015 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas de Bactérias / Reação em Cadeia da Polimerase em Tempo Real / Micobactérias não Tuberculosas Idioma: En Ano de publicação: 2015 Tipo de documento: Article