Long non-coding RNA TUG1 is up-regulated in hepatocellular carcinoma and promotes cell growth and apoptosis by epigenetically silencing of KLF2.

Huang, Ming-De; Chen, Wen-Ming; Qi, Fu-Zhen; Sun, Ming; Xu, Tong-Peng; Ma, Pei; Shu, Yong-Qian

Huang, Ming-De; Chen, Wen-Ming; Qi, Fu-Zhen; Sun, Ming; Xu, Tong-Peng; Ma, Pei; Shu, Yong-Qian.

Afiliação

Huang MD; Department of Medical Oncology, Huai'an First People's Hospital, Nanjing Medical University, Huai'an City, Jiangsu Province, 223301, People's Republic of China.
Chen WM; Department of Oncology, Jining No.1 People's Hospital, No.6, Jiankang Road, Jining City, Shandong Province, 272011, People's Republic of China.
Qi FZ; Department of Hepatopancreatobiliary Surgery, Huai'an First People's Hospital, Nanjing Medical University, Huai'an City, Jiangsu Province, 223300, People's Republic of China.
Sun M; Department of Biochemistry and Molecular Biology, Nanjing Medical University, Nanjing City, Jiangsu Province, People's Republic of China.
Xu TP; Department of Oncology, First Affiliated Hospital, Nanjing Medical University, Nanjing City, Jiangsu Province, People's Republic of China.
Ma P; Department of Oncology, First Affiliated Hospital, Nanjing Medical University, Nanjing City, Jiangsu Province, People's Republic of China.
Shu YQ; Department of Oncology, First Affiliated Hospital, Nanjing Medical University, Nanjing City, Jiangsu Province, People's Republic of China. yongqian_shu@163.com.

Mol Cancer ; 14: 165, 2015 Sep 04.

Article em En | MEDLINE | ID: mdl-26336870

Assuntos

Carcinoma Hepatocelular/genética; Fatores de Transcrição Kruppel-Like/genética; Neoplasias Hepáticas/genética; RNA Longo não Codificante/biossíntese; Adulto; Idoso; Apoptose/genética; Carcinoma Hepatocelular/patologia; Proliferação de Células/genética; Metilação de DNA/genética; Repressão Epigenética/genética; Feminino; Regulação Neoplásica da Expressão Gênica; Técnicas de Silenciamento de Genes; Células Hep G2; Humanos; Fatores de Transcrição Kruppel-Like/biossíntese; Neoplasias Hepáticas/patologia; Masculino; Pessoa de Meia-Idade; Complexo Repressor Polycomb 2/genética; Regiões Promotoras Genéticas; RNA Longo não Codificante/genética

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Carcinoma Hepatocelular / Fatores de Transcrição Kruppel-Like / RNA Longo não Codificante / Neoplasias Hepáticas Idioma: En Ano de publicação: 2015 Tipo de documento: Article

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