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Cas9 gRNA engineering for genome editing, activation and repression.
Kiani, Samira; Chavez, Alejandro; Tuttle, Marcelle; Hall, Richard N; Chari, Raj; Ter-Ovanesyan, Dmitry; Qian, Jason; Pruitt, Benjamin W; Beal, Jacob; Vora, Suhani; Buchthal, Joanna; Kowal, Emma J K; Ebrahimkhani, Mohammad R; Collins, James J; Weiss, Ron; Church, George.
Afiliação
  • Kiani S; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.
  • Chavez A; Synthetic Biology Center, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.
  • Tuttle M; Wyss Institute for Biologically Inspired Engineering, Harvard University, Cambridge, Massachusetts, USA.
  • Hall RN; Department of Pathology, Massachusetts General Hospital, Boston, Massachusetts, USA.
  • Chari R; Department of Genetics, Harvard Medical School, Boston, Massachusetts, USA.
  • Ter-Ovanesyan D; Wyss Institute for Biologically Inspired Engineering, Harvard University, Cambridge, Massachusetts, USA.
  • Qian J; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.
  • Pruitt BW; Synthetic Biology Center, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.
  • Beal J; Department of Genetics, Harvard Medical School, Boston, Massachusetts, USA.
  • Vora S; Wyss Institute for Biologically Inspired Engineering, Harvard University, Cambridge, Massachusetts, USA.
  • Buchthal J; Department of Genetics, Harvard Medical School, Boston, Massachusetts, USA.
  • Kowal EJ; Wyss Institute for Biologically Inspired Engineering, Harvard University, Cambridge, Massachusetts, USA.
  • Ebrahimkhani MR; Department of Genetics, Harvard Medical School, Boston, Massachusetts, USA.
  • Collins JJ; Wyss Institute for Biologically Inspired Engineering, Harvard University, Cambridge, Massachusetts, USA.
  • Weiss R; Raytheon BBN Technologies, Cambridge, Massachusetts, USA.
  • Church G; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.
Nat Methods ; 12(11): 1051-4, 2015 Nov.
Article em En | MEDLINE | ID: mdl-26344044
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: RNA Guia de Cinetoplastídeos / Sistemas CRISPR-Cas Idioma: En Ano de publicação: 2015 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: RNA Guia de Cinetoplastídeos / Sistemas CRISPR-Cas Idioma: En Ano de publicação: 2015 Tipo de documento: Article