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Selective targeting of JAK/STAT signaling is potentiated by Bcl-xL blockade in IL-2-dependent adult T-cell leukemia.
Zhang, Meili; Mathews Griner, Lesley A; Ju, Wei; Duveau, Damien Y; Guha, Rajarshi; Petrus, Michael N; Wen, Bernard; Maeda, Michiyuki; Shinn, Paul; Ferrer, Marc; Conlon, Kevin D; Bamford, Richard N; O'Shea, John J; Thomas, Craig J; Waldmann, Thomas A.
Afiliação
  • Zhang M; Lymphoid Malignancies Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892; Laboratory Animal Science Program, Leidos Biomedical Research, Inc., Frederick, MD 21702;
  • Mathews Griner LA; Division of Preclinical Innovation, National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD 20850;
  • Ju W; Lymphoid Malignancies Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892;
  • Duveau DY; Division of Preclinical Innovation, National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD 20850;
  • Guha R; Division of Preclinical Innovation, National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD 20850;
  • Petrus MN; Lymphoid Malignancies Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892;
  • Wen B; Lymphoid Malignancies Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892;
  • Maeda M; Institute for Virus Research, Kyoto University, Sakyo-ku, Kyoto 606-8507, Japan;
  • Shinn P; Division of Preclinical Innovation, National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD 20850;
  • Ferrer M; Division of Preclinical Innovation, National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD 20850;
  • Conlon KD; Lymphoid Malignancies Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892;
  • Bamford RN; Transponics, Jacobus, PA 17347;
  • O'Shea JJ; Molecular Immunology and Inflammation Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD 20892.
  • Thomas CJ; Division of Preclinical Innovation, National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD 20850; tawald@helix.nih.gov craigt@mail.nih.gov.
  • Waldmann TA; Lymphoid Malignancies Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892; tawald@helix.nih.gov craigt@mail.nih.gov.
Proc Natl Acad Sci U S A ; 112(40): 12480-5, 2015 Oct 06.
Article em En | MEDLINE | ID: mdl-26396258
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Leucemia-Linfoma de Células T do Adulto / Interleucina-2 / Fatores de Transcrição STAT / Proteína bcl-X / Janus Quinases Idioma: En Ano de publicação: 2015 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Leucemia-Linfoma de Células T do Adulto / Interleucina-2 / Fatores de Transcrição STAT / Proteína bcl-X / Janus Quinases Idioma: En Ano de publicação: 2015 Tipo de documento: Article