Efficacy of plasmapheresis for the treatment of pure red blood cell aplasia after allogeneic stem cell transplantation.
Transfusion
; 55(12): 2979-82, 2015 Dec.
Article
em En
| MEDLINE
| ID: mdl-26400406
ABSTRACT
BACKGROUND:
Pure red blood cell aplasia (PRCA) is a complication of ABO major-incompatible stem cell transplantation, likely due to the persistence of memory B lymphocytes of recipient origin, which produce hemagglutinins against ABO antigens on donor RBCs. At present no standard of care is established for this complication. CASE REPORT We report a case of PRCA after allogeneic bone marrow transplantation, successfully treated with plasma exchange (PEX) after failing erythropoietin administration.RESULTS:
The patient fully recovered from RBC aplasia.CONCLUSION:
This case suggests a role for PEX in the treatment of PRCA after allogeneic stem cell transplantation.
Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Plasmaferese
/
Aplasia Pura de Série Vermelha
/
Transplante de Células-Tronco Hematopoéticas
Idioma:
En
Ano de publicação:
2015
Tipo de documento:
Article