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Apoptosis induced by temozolomide and nimustine in glioblastoma cells is supported by JNK/c-Jun-mediated induction of the BH3-only protein BIM.
Tomicic, Maja T; Meise, Ruth; Aasland, Dorthe; Berte, Nancy; Kitzinger, Rebekka; Krämer, Oliver H; Kaina, Bernd; Christmann, Markus.
Afiliação
  • Tomicic MT; Department of Toxicology, University Medical Center Mainz, D-55131 Mainz, Germany.
  • Meise R; Department of Toxicology, University Medical Center Mainz, D-55131 Mainz, Germany.
  • Aasland D; Department of Toxicology, University Medical Center Mainz, D-55131 Mainz, Germany.
  • Berte N; Department of Toxicology, University Medical Center Mainz, D-55131 Mainz, Germany.
  • Kitzinger R; Department of Toxicology, University Medical Center Mainz, D-55131 Mainz, Germany.
  • Krämer OH; Department of Toxicology, University Medical Center Mainz, D-55131 Mainz, Germany.
  • Kaina B; Department of Toxicology, University Medical Center Mainz, D-55131 Mainz, Germany.
  • Christmann M; Department of Toxicology, University Medical Center Mainz, D-55131 Mainz, Germany.
Oncotarget ; 6(32): 33755-68, 2015 Oct 20.
Article em En | MEDLINE | ID: mdl-26418950

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Nimustina / Proteínas Proto-Oncogênicas / Proteínas Proto-Oncogênicas c-jun / Apoptose / Glioblastoma / Dacarbazina / MAP Quinase Quinase 4 / Proteínas Reguladoras de Apoptose / Proteínas de Membrana Idioma: En Ano de publicação: 2015 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Nimustina / Proteínas Proto-Oncogênicas / Proteínas Proto-Oncogênicas c-jun / Apoptose / Glioblastoma / Dacarbazina / MAP Quinase Quinase 4 / Proteínas Reguladoras de Apoptose / Proteínas de Membrana Idioma: En Ano de publicação: 2015 Tipo de documento: Article