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Thermoresponsive release of viable microfiltrated Circulating Tumor Cells (CTCs) for precision medicine applications.
Ao, Zheng; Parasido, Erika; Rawal, Siddarth; Williams, Anthony; Schlegel, Richard; Liu, Stephen; Albanese, Chris; Cote, Richard J; Agarwal, Ashutosh; Datar, Ram H.
Afiliação
  • Ao Z; Department of Pathology, University of Miami Miller School of Medicine, Miami, FL 33136, USA. A.agarwal2@miami.edu.
  • Parasido E; Departments of Oncology and Pathology, and the Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, USA.
  • Rawal S; Department of Pathology, University of Miami Miller School of Medicine, Miami, FL 33136, USA. A.agarwal2@miami.edu.
  • Williams A; Department of Pathology, University of Miami Miller School of Medicine, Miami, FL 33136, USA. A.agarwal2@miami.edu.
  • Schlegel R; Departments of Oncology and Pathology, and the Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, USA.
  • Liu S; Departments of Oncology and Pathology, and the Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, USA.
  • Albanese C; Departments of Oncology and Pathology, and the Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, USA.
  • Cote RJ; Department of Pathology, University of Miami Miller School of Medicine, Miami, FL 33136, USA. A.agarwal2@miami.edu.
  • Agarwal A; Department of Pathology, University of Miami Miller School of Medicine, Miami, FL 33136, USA. A.agarwal2@miami.edu and Department of Biomedical Engineering, University of Miami, USA.
  • Datar RH; Department of Pathology, University of Miami Miller School of Medicine, Miami, FL 33136, USA. A.agarwal2@miami.edu.
Lab Chip ; 15(22): 4277-82, 2015 Nov 21.
Article em En | MEDLINE | ID: mdl-26426331
ABSTRACT
Stimulus responsive release of Circulating Tumor Cells (CTCs), with high recovery rates from their capture platform, is highly desirable for off-chip analyses. Here, we present a temperature responsive polymer coating method to achieve both release as well as culture of viable CTCs captured from patient blood samples.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Temperatura / Técnicas Analíticas Microfluídicas / Medicina de Precisão / Células Neoplásicas Circulantes Idioma: En Ano de publicação: 2015 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Temperatura / Técnicas Analíticas Microfluídicas / Medicina de Precisão / Células Neoplásicas Circulantes Idioma: En Ano de publicação: 2015 Tipo de documento: Article