Inhibition of testicular embryonal carcinoma cell tumorigenicity by peroxisome proliferator-activated receptor-ß/Î´- and retinoic acid receptor-dependent mechanisms.

Yao, Pei-Li; Chen, Li Ping; Dobrzanski, Tomasz P; Phillips, Dylan A; Zhu, Bokai; Kang, Boo-Hyon; Gonzalez, Frank J; Peters, Jeffrey M

Yao, Pei-Li; Chen, Li Ping; Dobrzanski, Tomasz P; Phillips, Dylan A; Zhu, Bokai; Kang, Boo-Hyon; Gonzalez, Frank J; Peters, Jeffrey M.

Afiliação

Yao PL; Department of Veterinary and Biomedical Sciences, The Center of Molecular Toxicology and Carcinogenesis, The Pennsylvania State University, University Park, Pennsylvania, USA.
Chen LP; Department of Veterinary and Biomedical Sciences, The Center of Molecular Toxicology and Carcinogenesis, The Pennsylvania State University, University Park, Pennsylvania, USA.
Dobrzanski TP; Department of Veterinary and Biomedical Sciences, The Center of Molecular Toxicology and Carcinogenesis, The Pennsylvania State University, University Park, Pennsylvania, USA.
Phillips DA; Department of Veterinary and Biomedical Sciences, The Center of Molecular Toxicology and Carcinogenesis, The Pennsylvania State University, University Park, Pennsylvania, USA.
Zhu B; Department of Veterinary and Biomedical Sciences, The Center of Molecular Toxicology and Carcinogenesis, The Pennsylvania State University, University Park, Pennsylvania, USA.
Kang BH; Chemon Nonclinical Research Institute, Nampyeong-ro, Yangji-myeon, Cheoin-gu, Yongin-si, Gyeonggi-do, Korea.
Gonzalez FJ; Laboratory of Metabolism, National Cancer Institute, Bethesda, Maryland, USA.
Peters JM; Department of Veterinary and Biomedical Sciences, The Center of Molecular Toxicology and Carcinogenesis, The Pennsylvania State University, University Park, Pennsylvania, USA.

Oncotarget ; 6(34): 36319-37, 2015 Nov 03.

Article em En | MEDLINE | ID: mdl-26431381

Assuntos

PPAR delta/metabolismo; Receptores do Ácido Retinoico/metabolismo; Neoplasias Testiculares/metabolismo; Neoplasias Testiculares/patologia; Adolescente; Adulto; Carcinogênese; Diferenciação Celular; Linhagem Celular Tumoral; Proliferação de Células/fisiologia; Humanos; Masculino; Adulto Jovem

Palavras-chave

matrix metalloproteinase-2; peroxisome proliferator-activated receptor-ß/Î´; retinoic acid receptor; testicular embryonal carcinoma; tumorigenicity

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Testiculares / Receptores do Ácido Retinoico / PPAR delta Idioma: En Ano de publicação: 2015 Tipo de documento: Article

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