Cabozantinib (XL184) Inhibits Growth and Invasion of Preclinical TNBC Models.

Sameni, Mansoureh; Tovar, Elizabeth A; Essenburg, Curt J; Chalasani, Anita; Linklater, Erik S; Borgman, Andrew; Cherba, David M; Anbalagan, Arulselvi; Winn, Mary E; Graveel, Carrie R; Sloane, Bonnie F

Sameni, Mansoureh; Tovar, Elizabeth A; Essenburg, Curt J; Chalasani, Anita; Linklater, Erik S; Borgman, Andrew; Cherba, David M; Anbalagan, Arulselvi; Winn, Mary E; Graveel, Carrie R; Sloane, Bonnie F.

Afiliação

Sameni M; Department of Pharmacology, Wayne State University School of Medicine, Detroit, Michigan.
Tovar EA; Center for Cancer and Cell Biology, Van Andel Research Institute, Grand Rapids, Michigan.
Essenburg CJ; Center for Cancer and Cell Biology, Van Andel Research Institute, Grand Rapids, Michigan.
Chalasani A; Department of Pharmacology, Wayne State University School of Medicine, Detroit, Michigan.
Linklater ES; Center for Cancer and Cell Biology, Van Andel Research Institute, Grand Rapids, Michigan.
Borgman A; Bioinformatics and Biostatistics Core, Van Andel Research Institute, Grand Rapids, Michigan.
Cherba DM; Bioinformatics and Biostatistics Core, Van Andel Research Institute, Grand Rapids, Michigan.
Anbalagan A; Department of Pharmacology, Wayne State University School of Medicine, Detroit, Michigan.
Winn ME; Bioinformatics and Biostatistics Core, Van Andel Research Institute, Grand Rapids, Michigan.
Graveel CR; Center for Cancer and Cell Biology, Van Andel Research Institute, Grand Rapids, Michigan. carrie.graveel@vai.org.
Sloane BF; Department of Pharmacology, Wayne State University School of Medicine, Detroit, Michigan. Karmanos Cancer Institute, Wayne State University, Detroit, Michigan.

Clin Cancer Res ; 22(4): 923-34, 2016 Feb 15.

Article em En | MEDLINE | ID: mdl-26432786

Assuntos

Anilidas/farmacologia; Antineoplásicos/farmacologia; Neoplasias Pulmonares/tratamento farmacológico; Piridinas/farmacologia; Neoplasias de Mama Triplo Negativas/tratamento farmacológico; Animais; Linhagem Celular Tumoral; Proliferação de Células/efeitos dos fármacos; Técnicas de Cocultura; Feminino; Fibroblastos/efeitos dos fármacos; Fibroblastos/metabolismo; Humanos; Neoplasias Pulmonares/secundário; Camundongos Endogâmicos C3H; Camundongos SCID; Invasividade Neoplásica; Proteínas Proto-Oncogênicas c-met/metabolismo; Transdução de Sinais; Neoplasias de Mama Triplo Negativas/patologia; Carga Tumoral/efeitos dos fármacos; Ensaios Antitumorais Modelo de Xenoenxerto

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Piridinas / Neoplasias de Mama Triplo Negativas / Anilidas / Neoplasias Pulmonares / Antineoplásicos Idioma: En Ano de publicação: 2016 Tipo de documento: Article

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