Platelets made HLA deficient by acid treatment aggregate normally and escape destruction by complement and phagocytes in the presence of HLA antibodies.

Meinke, Stephan; Sandgren, Per; Mörtberg, Anette; Karlström, Cecilia; Kadri, Nadir; Wikman, Agneta; Höglund, Petter

Meinke, Stephan; Sandgren, Per; Mörtberg, Anette; Karlström, Cecilia; Kadri, Nadir; Wikman, Agneta; Höglund, Petter.

Afiliação

Meinke S; Center for Hematology and Regenerative Medicine (HERM), Department of Medicine Huddinge, Karolinska Institutet, Stockholm, Sweden.
Sandgren P; Clinic for Clinical Immunology and Transfusion Medicine, Karolinska University Hospital, Stockholm, Sweden.
Mörtberg A; Clinic for Clinical Immunology and Transfusion Medicine, Karolinska University Hospital, Stockholm, Sweden.
Karlström C; Clinic for Clinical Immunology and Transfusion Medicine, Karolinska University Hospital, Stockholm, Sweden.
Kadri N; Center for Hematology and Regenerative Medicine (HERM), Department of Medicine Huddinge, Karolinska Institutet, Stockholm, Sweden.
Wikman A; Clinic for Clinical Immunology and Transfusion Medicine, Karolinska University Hospital, Stockholm, Sweden.
Höglund P; Center for Hematology and Regenerative Medicine (HERM), Department of Medicine Huddinge, Karolinska Institutet, Stockholm, Sweden.

Transfusion ; 56(2): 370-82; quiz 369, 2016 Feb.

Article em En | MEDLINE | ID: mdl-26442787

Assuntos

Plaquetas/química; Ácido Cítrico/química; Proteínas do Sistema Complemento/química; Antígenos HLA/química; Fagócitos; Agregação Plaquetária; Plaquetas/citologia; Feminino; Humanos; Concentração de Íons de Hidrogênio; Masculino

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fagócitos / Plaquetas / Proteínas do Sistema Complemento / Agregação Plaquetária / Ácido Cítrico / Antígenos HLA Idioma: En Ano de publicação: 2016 Tipo de documento: Article

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