Nosology and Pathology of Langerhans Cell Histiocytosis.
Hematol Oncol Clin North Am
; 29(5): 799-823, 2015 Oct.
Article
em En
| MEDLINE
| ID: mdl-26461144
ABSTRACT
The classification of the histiocytoses has evolved based on new understanding of the cell of origin as a bone marrow precursor. Although the pathologic features of the histiocytoses have not changed per se, molecular genetic information now needs to be integrated into the diagnosis. The basic lesions of the most common histiocytoses, their patterns in different sites, and ancillary diagnostics are now just one part of the classification. As more is understood about the cell of origin and molecular biology of the histiocytoses, future classifications will be refined.
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Base de dados:
MEDLINE
Assunto principal:
Histiocitose de Células de Langerhans
Idioma:
En
Ano de publicação:
2015
Tipo de documento:
Article