The First Case of Total Dystrophic Onychomycosis Caused by Aspergillus clavatus Resistant to Antifungal Drugs.
Mycopathologia
; 181(3-4): 273-7, 2016 Apr.
Article
em En
| MEDLINE
| ID: mdl-26474550
ABSTRACT
Onychomycosis is a common fungal infection of nails which is mainly caused by dermatophyte species and less often by yeasts and non-dermatophyte molds. We present a case of onychomycosis due to Aspergillus clavatus for the first time worldwide. The patient was an immunocompetent 32-year-old woman who identified with Psoriasis of the nail. The presence of A. clavatus in a nail sample was confirmed using microscopic and culture analysis followed by PCR of the ß-tubulin gene. After antifungal susceptibility test, it is revealed that the isolate was resistant to the majority of common antifungal drugs, but finally the patient was treated with itraconazole 200 mg daily. A. clavatus and drug-resistant A. clavatus have not previously been reported from onychomycosis.
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MEDLINE
Assunto principal:
Aspergillus
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Onicomicose
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Itraconazol
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Farmacorresistência Fúngica Múltipla
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Dermatoses da Mão
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Antifúngicos
Idioma:
En
Ano de publicação:
2016
Tipo de documento:
Article