Synergistic Combination Chemotherapy of Camptothecin and Floxuridine through Self-Assembly of Amphiphilic Drug-Drug Conjugate.

Hu, Minxi; Huang, Ping; Wang, Yao; Su, Yue; Zhou, Linzhu; Zhu, Xinyuan; Yan, Deyue

Hu, Minxi; Huang, Ping; Wang, Yao; Su, Yue; Zhou, Linzhu; Zhu, Xinyuan; Yan, Deyue.

Afiliação

Hu M; School of Chemistry and Chemical Engineering, Shanghai Key Lab of Electrical Insulation and Thermal Aging, Shanghai Jiao Tong University , 800 Dongchuan Road, Shanghai 200240, P. R. China.
Huang P; School of Chemistry and Chemical Engineering, Shanghai Key Lab of Electrical Insulation and Thermal Aging, Shanghai Jiao Tong University , 800 Dongchuan Road, Shanghai 200240, P. R. China.
Wang Y; School of Chemistry and Chemical Engineering, Shanghai Key Lab of Electrical Insulation and Thermal Aging, Shanghai Jiao Tong University , 800 Dongchuan Road, Shanghai 200240, P. R. China.
Su Y; School of Chemistry and Chemical Engineering, Shanghai Key Lab of Electrical Insulation and Thermal Aging, Shanghai Jiao Tong University , 800 Dongchuan Road, Shanghai 200240, P. R. China.
Zhou L; School of Chemistry and Chemical Engineering, Shanghai Key Lab of Electrical Insulation and Thermal Aging, Shanghai Jiao Tong University , 800 Dongchuan Road, Shanghai 200240, P. R. China.
Zhu X; School of Chemistry and Chemical Engineering, Shanghai Key Lab of Electrical Insulation and Thermal Aging, Shanghai Jiao Tong University , 800 Dongchuan Road, Shanghai 200240, P. R. China.
Yan D; School of Chemistry and Chemical Engineering, Shanghai Key Lab of Electrical Insulation and Thermal Aging, Shanghai Jiao Tong University , 800 Dongchuan Road, Shanghai 200240, P. R. China.

Bioconjug Chem ; 26(12): 2497-506, 2015 Dec 16.

Article em En | MEDLINE | ID: mdl-26497258

Assuntos

Antineoplásicos/química; Antineoplásicos/farmacologia; Camptotecina/química; Camptotecina/farmacologia; Neoplasias Colorretais/tratamento farmacológico; Floxuridina/química; Floxuridina/farmacologia; Antineoplásicos/síntese química; Antineoplásicos/farmacocinética; Apoptose/efeitos dos fármacos; Camptotecina/síntese química; Camptotecina/farmacocinética; Linhagem Celular Tumoral; Proliferação de Células/efeitos dos fármacos; Colo/efeitos dos fármacos; Colo/patologia; Neoplasias Colorretais/patologia; Sinergismo Farmacológico; Floxuridina/síntese química; Floxuridina/farmacocinética; Humanos; Nanopartículas/química; Reto/efeitos dos fármacos; Reto/patologia; Distribuição Tecidual

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Camptotecina / Neoplasias Colorretais / Floxuridina / Antineoplásicos Idioma: En Ano de publicação: 2015 Tipo de documento: Article

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