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Guanine nucleotide binding to the Bateman domain mediates the allosteric inhibition of eukaryotic IMP dehydrogenases.
Buey, Rubén M; Ledesma-Amaro, Rodrigo; Velázquez-Campoy, Adrián; Balsera, Mónica; Chagoyen, Mónica; de Pereda, José M; Revuelta, José L.
Afiliação
  • Buey RM; Metabolic Engineering Group, Dpto. Microbiología y Genética. Universidad de Salamanca, Campus Miguel de Unamuno, Edificio Departamental, Salamanca 37007, Spain.
  • Ledesma-Amaro R; Metabolic Engineering Group, Dpto. Microbiología y Genética. Universidad de Salamanca, Campus Miguel de Unamuno, Edificio Departamental, Salamanca 37007, Spain.
  • Velázquez-Campoy A; Institute of Biocomputation and Physics of Complex Systems (BIFI), Joint Unit IQFR-CSIC-BIFI, Universidad de Zaragoza, C/Mariano Esquillor, Zaragoza 50018, Spain.
  • Balsera M; Department of Biochemistry and Molecular and Cell Biology, University of Zaragoza, Zaragoza 50009, Spain.
  • Chagoyen M; Instituto de Investigaciones Sanitarias de Aragón (IIS-A), Zaragoza 50009, Spain.
  • de Pereda JM; Fundación ARAID, Government of Aragón, Zaragoza 50018, Spain.
  • Revuelta JL; Department Abiotic Stress, Instituto de Recursos Naturales y Agrobiología (IRNASA-CSIC), Cordel de Merinas 40-52, Salamanca 37008, Spain.
Nat Commun ; 6: 8923, 2015 Nov 12.
Article em En | MEDLINE | ID: mdl-26558346
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ascomicetos / Guanosina Difosfato / Guanosina Trifosfato / IMP Desidrogenase Idioma: En Ano de publicação: 2015 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ascomicetos / Guanosina Difosfato / Guanosina Trifosfato / IMP Desidrogenase Idioma: En Ano de publicação: 2015 Tipo de documento: Article