CHIP-mediated degradation of transglutaminase 2 negatively regulates tumor growth and angiogenesis in renal cancer.

Min, B; Park, H; Lee, S; Li, Y; Choi, J-M; Lee, J Y; Kim, J; Choi, Y D; Kwon, Y-G; Lee, H-W; Bae, S-C; Yun, C-O; Chung, K C

Min, B; Park, H; Lee, S; Li, Y; Choi, J-M; Lee, J Y; Kim, J; Choi, Y D; Kwon, Y-G; Lee, H-W; Bae, S-C; Yun, C-O; Chung, K C.

Afiliação

Min B; Department of Systems Biology, College of Life Science and Biotechnology, Yonsei University, Seoul, Republic of Korea.
Park H; Department of Biochemistry, College of Life Science and Biotechnology, Yonsei University, Seoul, Republic of Korea.
Lee S; Department of Biochemistry, College of Life Science and Biotechnology, Yonsei University, Seoul, Republic of Korea.
Li Y; Department of Bioengineering, College of Engineering, Hanyang University, Seoul, Republic of Korea.
Choi JM; Department of Biochemistry, College of Life Science and Biotechnology, Yonsei University, Seoul, Republic of Korea.
Lee JY; Department of Urology, Yonsei University College of Medicine, Seoul, Republic of Korea.
Kim J; Department of Anatomy, School of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
Choi YD; Department of Urology, Yonsei University College of Medicine, Seoul, Republic of Korea.
Kwon YG; Department of Biochemistry, College of Life Science and Biotechnology, Yonsei University, Seoul, Republic of Korea.
Lee HW; Department of Biochemistry, College of Life Science and Biotechnology, Yonsei University, Seoul, Republic of Korea.
Bae SC; Department of Biochemistry, College of Medicine, Chungbuk National University, Cheongju, Republic of Korea.
Yun CO; Department of Bioengineering, College of Engineering, Hanyang University, Seoul, Republic of Korea.
Chung KC; Department of Systems Biology, College of Life Science and Biotechnology, Yonsei University, Seoul, Republic of Korea.

Oncogene ; 35(28): 3718-28, 2016 07 14.

Article em En | MEDLINE | ID: mdl-26568304

Assuntos

Carcinoma de Células Renais/metabolismo; Proteínas de Ligação ao GTP/metabolismo; Neoplasias Renais/metabolismo; Neovascularização Patológica/metabolismo; Transglutaminases/metabolismo; Ubiquitina-Proteína Ligases/metabolismo; Animais; Carcinoma de Células Renais/irrigação sanguínea; Carcinoma de Células Renais/genética; Linhagem Celular Tumoral; Proteínas de Ligação ao GTP/genética; Regulação Neoplásica da Expressão Gênica; Células HEK293; Humanos; Immunoblotting; Imuno-Histoquímica; Neoplasias Renais/irrigação sanguínea; Neoplasias Renais/genética; Masculino; Camundongos Endogâmicos C57BL; Camundongos Nus; Neovascularização Patológica/genética; Neovascularização Patológica/patologia; Complexo de Endopeptidases do Proteassoma/metabolismo; Ligação Proteica; Proteína 2 Glutamina gama-Glutamiltransferase; Proteólise; Transglutaminases/genética; Transplante Heterólogo; Ubiquitina-Proteína Ligases/genética; Ubiquitinação

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Carcinoma de Células Renais / Transglutaminases / Proteínas de Ligação ao GTP / Ubiquitina-Proteína Ligases / Neoplasias Renais / Neovascularização Patológica Idioma: En Ano de publicação: 2016 Tipo de documento: Article

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