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Translational profiling identifies a cascade of damage initiated in motor neurons and spreading to glia in mutant SOD1-mediated ALS.
Sun, Shuying; Sun, Ying; Ling, Shuo-Chien; Ferraiuolo, Laura; McAlonis-Downes, Melissa; Zou, Yiyang; Drenner, Kevin; Wang, Yin; Ditsworth, Dara; Tokunaga, Seiya; Kopelevich, Alex; Kaspar, Brian K; Lagier-Tourenne, Clotilde; Cleveland, Don W.
Afiliação
  • Sun S; Ludwig Institute for Cancer Research, University of California at San Diego, La Jolla, CA 92093; Department of Cellular and Molecular Medicine, University of California at San Diego, La Jolla, CA 92093;
  • Sun Y; Ludwig Institute for Cancer Research, University of California at San Diego, La Jolla, CA 92093; Department of Cellular and Molecular Medicine, University of California at San Diego, La Jolla, CA 92093;
  • Ling SC; Ludwig Institute for Cancer Research, University of California at San Diego, La Jolla, CA 92093; Department of Cellular and Molecular Medicine, University of California at San Diego, La Jolla, CA 92093;
  • Ferraiuolo L; The Research Institute at Nationwide Children's Hospital, Department of Neuroscience, The Ohio State University, Columbus, OH 43205;
  • McAlonis-Downes M; Ludwig Institute for Cancer Research, University of California at San Diego, La Jolla, CA 92093; Department of Cellular and Molecular Medicine, University of California at San Diego, La Jolla, CA 92093;
  • Zou Y; Department of Cellular and Molecular Medicine, University of California at San Diego, La Jolla, CA 92093;
  • Drenner K; Ludwig Institute for Cancer Research, University of California at San Diego, La Jolla, CA 92093; Department of Cellular and Molecular Medicine, University of California at San Diego, La Jolla, CA 92093;
  • Wang Y; Ludwig Institute for Cancer Research, University of California at San Diego, La Jolla, CA 92093; Department of Cellular and Molecular Medicine, University of California at San Diego, La Jolla, CA 92093;
  • Ditsworth D; Ludwig Institute for Cancer Research, University of California at San Diego, La Jolla, CA 92093; Department of Cellular and Molecular Medicine, University of California at San Diego, La Jolla, CA 92093;
  • Tokunaga S; Ludwig Institute for Cancer Research, University of California at San Diego, La Jolla, CA 92093; Department of Cellular and Molecular Medicine, University of California at San Diego, La Jolla, CA 92093;
  • Kopelevich A; Department of Cellular and Molecular Medicine, University of California at San Diego, La Jolla, CA 92093;
  • Kaspar BK; The Research Institute at Nationwide Children's Hospital, Department of Neuroscience, The Ohio State University, Columbus, OH 43205;
  • Lagier-Tourenne C; Ludwig Institute for Cancer Research, University of California at San Diego, La Jolla, CA 92093; Department of Neurosciences, University of California at San Diego, La Jolla, CA 92093.
  • Cleveland DW; Ludwig Institute for Cancer Research, University of California at San Diego, La Jolla, CA 92093; Department of Cellular and Molecular Medicine, University of California at San Diego, La Jolla, CA 92093; Department of Neurosciences, University of California at San Diego, La Jolla, CA 92093 dcleveland
Proc Natl Acad Sci U S A ; 112(50): E6993-7002, 2015 Dec 15.
Article em En | MEDLINE | ID: mdl-26621731
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Superóxido Dismutase / Biossíntese de Proteínas / Neuroglia / Perfilação da Expressão Gênica / Esclerose Lateral Amiotrófica / Neurônios Motores / Mutação Idioma: En Ano de publicação: 2015 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Superóxido Dismutase / Biossíntese de Proteínas / Neuroglia / Perfilação da Expressão Gênica / Esclerose Lateral Amiotrófica / Neurônios Motores / Mutação Idioma: En Ano de publicação: 2015 Tipo de documento: Article