Tumor-selective peptide-carrier delivery of Paclitaxel increases in vivo activity of the drug.

Brunetti, Jlenia; Pillozzi, Serena; Falciani, Chiara; Depau, Lorenzo; Tenori, Eleonora; Scali, Silvia; Lozzi, Luisa; Pini, Alessandro; Arcangeli, Annarosa; Menichetti, Stefano; Bracci, Luisa

Brunetti, Jlenia; Pillozzi, Serena; Falciani, Chiara; Depau, Lorenzo; Tenori, Eleonora; Scali, Silvia; Lozzi, Luisa; Pini, Alessandro; Arcangeli, Annarosa; Menichetti, Stefano; Bracci, Luisa.

Afiliação

Brunetti J; University of Siena, Department of Medical Biotechnologies, Siena, 53100, Italy.
Pillozzi S; University of Florence, Department of Experimental and Clinical Medicine, Florence, 50139, Italy.
Falciani C; SetLance srl, Toscana Life Sciences, Siena, 53100, Italy.
Depau L; University of Siena, Department of Medical Biotechnologies, Siena, 53100, Italy.
Tenori E; University of Florence, Department of Chemistry, Florence, 50019, Italy.
Scali S; University of Siena, Department of Medical Biotechnologies, Siena, 53100, Italy.
Lozzi L; University of Siena, Department of Medical Biotechnologies, Siena, 53100, Italy.
Pini A; University of Siena, Department of Medical Biotechnologies, Siena, 53100, Italy.
Arcangeli A; University of Florence, Department of Experimental and Clinical Medicine, Florence, 50139, Italy.
Menichetti S; University of Florence, Department of Chemistry, Florence, 50019, Italy.
Bracci L; University of Siena, Department of Medical Biotechnologies, Siena, 53100, Italy.

Sci Rep ; 5: 17736, 2015 Dec 02.

Article em En | MEDLINE | ID: mdl-26626158

Assuntos

Neoplasias da Mama/tratamento farmacológico; Portadores de Fármacos/farmacologia; Neoplasias Mamárias Experimentais/tratamento farmacológico; Neoplasias Ovarianas/tratamento farmacológico; Paclitaxel/farmacologia; Peptídeos/farmacologia; Animais; Neoplasias da Mama/metabolismo; Neoplasias da Mama/patologia; Portadores de Fármacos/química; Feminino; Humanos; Neoplasias Mamárias Experimentais/metabolismo; Neoplasias Mamárias Experimentais/patologia; Camundongos; Camundongos Nus; Neoplasias Ovarianas/metabolismo; Neoplasias Ovarianas/patologia; Paclitaxel/química; Peptídeos/química; Ensaios Antitumorais Modelo de Xenoenxerto

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Ovarianas / Peptídeos / Neoplasias da Mama / Portadores de Fármacos / Paclitaxel / Neoplasias Mamárias Experimentais Idioma: En Ano de publicação: 2015 Tipo de documento: Article

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