Mindfulness in the Maintenance of Cognitive Capacities in Alzheimer's Disease: A Randomized Clinical Trial.
J Alzheimers Dis
; 50(1): 217-32, 2016.
Article
em En
| MEDLINE
| ID: mdl-26639952
ABSTRACT
BACKGROUND:
The Canary Islands longitudinal study on non-pharmacological treatments showed the overall effectiveness of mindfulness in Alzheimer's disease (AD). However, no specific data on the maintenance of cognitive capacities were presented.OBJECTIVE:
To determine whether the practice of mindfulness modifies the course of cognitive impairment in AD.DESIGN:
Longitudinal, non-inferiority and equivalence, randomized clinical trial, repeated-measures design, with three experimental groups and one control group.PARTICIPANTS:
Patients with AD who voluntarily attended the Lidia García Foundation (nâ=â502). Only those who were treated with donepezil and MMSE ≥18 were included (nâ=â120). INTERVENTION Over a two-year period, each group carried out three weekly sessions of stimulation based on mindfulness, cognitive stimulation therapy, and progressive muscle relaxation.MEASURES:
Cognitive assessment CAMDEX-R (MMSE and CAMCOG). STATISTICALANALYSIS:
Repeated-measures ANOVA (pâ< â0.05) and the effect size Cohen's d were performed.RESULTS:
The mindfulness group showed significant scores compared with the control and muscle relaxation groups (pâ< â0.05), while mindfulness and cognitive stimulation therapy were equivalent (p≥0.05). Group cognitive stimulation evolved better than the control (pâ< â0.05) group but not better than the muscle relaxation group (p≥0.05). The effect size compared over two years was large for the mindfulness group (p≥0.80), moderate for the relaxation group (p≥0.50), and low for the cognitive stimulation group (p≥0.20).CONCLUSION:
The practice of mindfulness maintained cognitive function over a period of two years. This longitudinal study suggests that mindfulness can be used as a non-pharmacological treatment to slow cognitive impairment in AD.Palavras-chave
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Base de dados:
MEDLINE
Assunto principal:
Transtornos Cognitivos
/
Doença de Alzheimer
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Atenção Plena
Idioma:
En
Ano de publicação:
2016
Tipo de documento:
Article