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Perturbation of the Conformational Dynamics of an Active-Site Loop Alters Enzyme Activity.
Gagné, Donald; French, Rachel L; Narayanan, Chitra; Simonovic, Miljan; Agarwal, Pratul K; Doucet, Nicolas.
Afiliação
  • Gagné D; INRS-Institut Armand-Frappier, Université du Québec, 531 Boulevard des Prairies, Laval, QC H7V 1B7, Canada.
  • French RL; Department of Biochemistry and Molecular Genetics, University of Illinois at Chicago, 900 South Ashland, Chicago, IL 60607, USA.
  • Narayanan C; INRS-Institut Armand-Frappier, Université du Québec, 531 Boulevard des Prairies, Laval, QC H7V 1B7, Canada.
  • Simonovic M; Department of Biochemistry and Molecular Genetics, University of Illinois at Chicago, 900 South Ashland, Chicago, IL 60607, USA.
  • Agarwal PK; Computational Biology Institute and Computer Science and Mathematics Division, Oak Ridge National Laboratory, 1 Bethel Valley Road, Oak Ridge, TN 37830, USA; Department of Biochemistry, Cellular and Molecular Biology, University of Tennessee, Knoxville, TN 37996, USA.
  • Doucet N; INRS-Institut Armand-Frappier, Université du Québec, 531 Boulevard des Prairies, Laval, QC H7V 1B7, Canada; PROTEO, the Québec Network for Research on Protein Function, Engineering, and Applications, 1045 Avenue de la Médecine, Université Laval, QC G1V 0A6, Canada; GRASP, the Groupe de Recherche Axé
Structure ; 23(12): 2256-2266, 2015 Dec 01.
Article em En | MEDLINE | ID: mdl-26655472
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ribonuclease Pancreático / Domínio Catalítico / Simulação de Dinâmica Molecular Idioma: En Ano de publicação: 2015 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ribonuclease Pancreático / Domínio Catalítico / Simulação de Dinâmica Molecular Idioma: En Ano de publicação: 2015 Tipo de documento: Article