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Interleukin-1 antagonism moderates the inflammatory state associated with Type 1 diabetes during clinical trials conducted at disease onset.
Cabrera, Susanne M; Wang, Xujing; Chen, Yi-Guang; Jia, Shuang; Kaldunski, Mary L; Greenbaum, Carla J; Mandrup-Poulsen, Thomas; Hessner, Martin J.
Afiliação
  • Cabrera SM; The Max McGee National Research Center for Juvenile Diabetes, Children's Research Institute of Children's Hospital of Wisconsin, and Department of Pediatrics at the Medical College of Wisconsin, Milwaukee, WI, USA.
  • Wang X; Systems Biology Center, the National Heart, Lung, and Blood Institute, the National Institutes of Health, Bethesda, MD, USA.
  • Chen YG; The Max McGee National Research Center for Juvenile Diabetes, Children's Research Institute of Children's Hospital of Wisconsin, and Department of Pediatrics at the Medical College of Wisconsin, Milwaukee, WI, USA.
  • Jia S; The Max McGee National Research Center for Juvenile Diabetes, Children's Research Institute of Children's Hospital of Wisconsin, and Department of Pediatrics at the Medical College of Wisconsin, Milwaukee, WI, USA.
  • Kaldunski ML; The Max McGee National Research Center for Juvenile Diabetes, Children's Research Institute of Children's Hospital of Wisconsin, and Department of Pediatrics at the Medical College of Wisconsin, Milwaukee, WI, USA.
  • Greenbaum CJ; Diabetes Research Program, Benaroya Research Institute, Seattle, WA, USA.
  • Mandrup-Poulsen T; Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Eur J Immunol ; 46(4): 1030-46, 2016 Apr.
Article em En | MEDLINE | ID: mdl-26692253

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Diabetes Mellitus Tipo 1 / Proteína Antagonista do Receptor de Interleucina 1 / Interleucina-1alfa / Interleucina-1beta / Inflamação / Anticorpos Monoclonais Idioma: En Ano de publicação: 2016 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Diabetes Mellitus Tipo 1 / Proteína Antagonista do Receptor de Interleucina 1 / Interleucina-1alfa / Interleucina-1beta / Inflamação / Anticorpos Monoclonais Idioma: En Ano de publicação: 2016 Tipo de documento: Article