Anti-Obesity Effect of 6,8-Diprenylgenistein, an Isoflavonoid of Cudrania tricuspidata Fruits in High-Fat Diet-Induced Obese Mice.

Jo, Yang Hee; Choi, Kyeong-Mi; Liu, Qing; Kim, Seon Beom; Ji, Hyeong-Jin; Kim, Myounghwan; Shin, Sang-Kyung; Do, Seon-Gil; Shin, Eunju; Jung, Gayoung; Yoo, Hwan-Soo; Hwang, Bang Yeon; Lee, Mi Kyeong

Jo, Yang Hee; Choi, Kyeong-Mi; Liu, Qing; Kim, Seon Beom; Ji, Hyeong-Jin; Kim, Myounghwan; Shin, Sang-Kyung; Do, Seon-Gil; Shin, Eunju; Jung, Gayoung; Yoo, Hwan-Soo; Hwang, Bang Yeon; Lee, Mi Kyeong.

Afiliação

Jo YH; College of Pharmacy, Chungbuk National University, Cheongju, Chungbuk 28644, Korea. qow0125@naver.com.
Choi KM; College of Pharmacy, Chungbuk National University, Cheongju, Chungbuk 28644, Korea. mirine0101@hanmail.net.
Liu Q; College of Pharmacy, Chungbuk National University, Cheongju, Chungbuk 28644, Korea. liuqing7115@hotmail.com.
Kim SB; College of Pharmacy, Chungbuk National University, Cheongju, Chungbuk 28644, Korea. suntiger85@hanmail.net.
Ji HJ; Laboratory Animal Research Center, Chungbuk National University, Cheongju, Chungbuk 28644, Korea. jihjin@chungbuk.ac.kr.
Kim M; Laboratory Animal Research Center, Chungbuk National University, Cheongju, Chungbuk 28644, Korea. mhkim3340@naver.com.
Shin SK; Laboratory Animal Research Center, Chungbuk National University, Cheongju, Chungbuk 28644, Korea. skshin@chungbuk.ac.kr.
Do SG; Wellness R&D Center, Univera, Inc., Seoul 05014, Korea. sgildo@univera.com.
Shin E; Wellness R&D Center, Univera, Inc., Seoul 05014, Korea. Ejayshin@univera.com.
Jung G; Wellness R&D Center, Univera, Inc., Seoul 05014, Korea. gayoung@univera.com.
Yoo HS; College of Pharmacy, Chungbuk National University, Cheongju, Chungbuk 28644, Korea. yoohs@chungbuk.ac.kr.
Hwang BY; College of Pharmacy, Chungbuk National University, Cheongju, Chungbuk 28644, Korea. byhwang@chungbuk.ac.kr.
Lee MK; College of Pharmacy, Chungbuk National University, Cheongju, Chungbuk 28644, Korea. mklee@chungbuk.ac.kr.

Nutrients ; 7(12): 10480-90, 2015 Dec 15.

Article em En | MEDLINE | ID: mdl-26694457

Assuntos

Fármacos Antiobesidade/farmacologia; Frutas/química; Genisteína/análogos & derivados; Isoflavonas/farmacologia; Moraceae/química; Obesidade/tratamento farmacológico; Proteínas Quinases Ativadas por AMP/genética; Proteínas Quinases Ativadas por AMP/metabolismo; Acetil-CoA Carboxilase/genética; Acetil-CoA Carboxilase/metabolismo; Adiponectina/metabolismo; Tecido Adiposo/efeitos dos fármacos; Tecido Adiposo/metabolismo; Animais; Proteína alfa Estimuladora de Ligação a CCAAT/genética; Proteína alfa Estimuladora de Ligação a CCAAT/metabolismo; Dieta Hiperlipídica; Regulação da Expressão Gênica; Genisteína/farmacologia; Hidroximetilglutaril-CoA Redutases/genética; Hidroximetilglutaril-CoA Redutases/metabolismo; Leptina/metabolismo; Fígado/efeitos dos fármacos; Fígado/metabolismo; Masculino; Camundongos; Camundongos Endogâmicos C57BL; Camundongos Obesos; PPAR gama/genética; PPAR gama/metabolismo; Extratos Vegetais/farmacologia

Palavras-chave

6,8-Diprenylgenistein (DPG); AMPK; Cudrania tricuspidata; high-fat diet-induced obesity; lipid profile

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fármacos Antiobesidade / Genisteína / Moraceae / Frutas / Isoflavonas / Obesidade Idioma: En Ano de publicação: 2015 Tipo de documento: Article

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