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8-Hydroxyquinoline-based inhibitors of the Rce1 protease disrupt Ras membrane localization in human cells.
Mohammed, Idrees; Hampton, Shahienaz E; Ashall, Louise; Hildebrandt, Emily R; Kutlik, Robert A; Manandhar, Surya P; Floyd, Brandon J; Smith, Haley E; Dozier, Jonathan K; Distefano, Mark D; Schmidt, Walter K; Dore, Timothy M.
Afiliação
  • Mohammed I; New York University Abu Dhabi, PO Box 129188, Abu Dhabi, United Arab Emirates.
  • Hampton SE; New York University Abu Dhabi, PO Box 129188, Abu Dhabi, United Arab Emirates.
  • Ashall L; New York University Abu Dhabi, PO Box 129188, Abu Dhabi, United Arab Emirates.
  • Hildebrandt ER; Department of Biochemistry & Molecular Biology, University of Georgia, Athens, GA 30602, United States.
  • Kutlik RA; Department of Chemistry, University of Georgia, Athens, GA 30602, United States.
  • Manandhar SP; Department of Biochemistry & Molecular Biology, University of Georgia, Athens, GA 30602, United States.
  • Floyd BJ; Department of Chemistry, University of Georgia, Athens, GA 30602, United States.
  • Smith HE; New York University Abu Dhabi, PO Box 129188, Abu Dhabi, United Arab Emirates.
  • Dozier JK; Department of Chemistry, University of Minnesota, Minneapolis, MN 55455, United States.
  • Distefano MD; Department of Chemistry, University of Minnesota, Minneapolis, MN 55455, United States.
  • Schmidt WK; Department of Biochemistry & Molecular Biology, University of Georgia, Athens, GA 30602, United States.
  • Dore TM; New York University Abu Dhabi, PO Box 129188, Abu Dhabi, United Arab Emirates; Department of Chemistry, University of Georgia, Athens, GA 30602, United States. Electronic address: timothy.dore@nyu.edu.
Bioorg Med Chem ; 24(2): 160-78, 2016 Jan 15.
Article em En | MEDLINE | ID: mdl-26706114
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Endopeptidases / Inibidores de Proteases / Oxiquinolina / Proteínas ras Idioma: En Ano de publicação: 2016 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Endopeptidases / Inibidores de Proteases / Oxiquinolina / Proteínas ras Idioma: En Ano de publicação: 2016 Tipo de documento: Article