The fusion rate of demineralized bone matrix compared with autogenous iliac bone graft for long multi-segment posterolateral spinal fusion.
BMC Musculoskelet Disord
; 17: 3, 2016 Jan 05.
Article
em En
| MEDLINE
| ID: mdl-26728876
ABSTRACT
BACKGROUND:
Although autogenous iliac bone graft (AIBG) remains the gold standard for spine fusion, harvesting morbidity has prompted the search for alternatives especially for multi-segment fusion. This study aimed to evaluate the efficacy of using demineralized bone matrix (DBM) as a substitute of AIBG for long instrumented posterolateral fusion (⧠three-level fusion).METHODS:
A total of 47 consecutive patients underwent laminectomy decompression, and multi-level instrumented posterolateral fusions were reviewed. Group 1 comprised 26 patients having DBM with autologous laminectomy bone (ALB). Group 2 consisted of 21 patients having AIBG with ALB. The fusion success evaluation was based on findings using the 12-month anteroposterior and dynamic plain radiographs.RESULTS:
Gender, age, and the number of fusion levels were similar for both groups. 21 of 26 (80.8%) patients in group 1 and 18 of 21 (85.7%) patients in group 2 were observed to achieve solid bony fusion. There was no statistical difference in the fusion success (p = 0.72). Blood loss was significantly more in group 2 (p = 0.02). The duration of the hospital stays and operative times being longer for group 2, but the difference was not significant.CONCLUSIONS:
DBM combined with ALB and osteoconductive materials is as effective as an autologous iliac bone graft with respect to long multi-segment posterolateral fusion success. DBM can be used as an effective bone graft substitute and may decrease morbidities associated with iliac bone graft harvest.
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Base de dados:
MEDLINE
Assunto principal:
Fusão Vertebral
/
Materiais Biocompatíveis
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Matriz Óssea
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Transplante Ósseo
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Técnica de Desmineralização Óssea
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Ílio
Idioma:
En
Ano de publicação:
2016
Tipo de documento:
Article