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A novel liposomal Clodronate depletes tumor-associated macrophages in primary and metastatic melanoma: Anti-angiogenic and anti-tumor effects.
Piaggio, F; Kondylis, V; Pastorino, F; Di Paolo, D; Perri, P; Cossu, I; Schorn, F; Marinaccio, C; Murgia, D; Daga, A; Raggi, F; Loi, M; Emionite, L; Ognio, E; Pasparakis, M; Ribatti, D; Ponzoni, M; Brignole, C.
Afiliação
  • Piaggio F; Laboratory of Oncology, Istituto Giannina Gaslini, 16147 Genoa, Italy.
  • Kondylis V; Institute for Genetics, University of Cologne, 50674 Cologne, Germany; Centre for Molecular Medicine (CMMC), University of Cologne, 50931 Cologne, Germany; Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, 50931 Cologne, Germany.
  • Pastorino F; Laboratory of Oncology, Istituto Giannina Gaslini, 16147 Genoa, Italy.
  • Di Paolo D; Laboratory of Oncology, Istituto Giannina Gaslini, 16147 Genoa, Italy.
  • Perri P; Laboratory of Oncology, Istituto Giannina Gaslini, 16147 Genoa, Italy.
  • Cossu I; Laboratory of Oncology, Istituto Giannina Gaslini, 16147 Genoa, Italy.
  • Schorn F; Institute for Genetics, University of Cologne, 50674 Cologne, Germany; Centre for Molecular Medicine (CMMC), University of Cologne, 50931 Cologne, Germany; Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, 50931 Cologne, Germany.
  • Marinaccio C; Department of Basic Medical Sciences, Neurosciences and Sensory Organs, University of Bari Medical School, 70124 Bari, Italy.
  • Murgia D; Department of Pathology, Istituto Giannina Gaslini, 16147 Genoa, Italy.
  • Daga A; Laboratorio di Trasferimento Genico, IRCCS Azienda Ospedaliera Universitaria San Martino-IST Istituto Nazionale per la Ricerca sul Cancro, 16132 Genoa, Italy.
  • Raggi F; Laboratory of Molecular Biology, Istituto Giannina Gaslini, 16147 Genoa, Italy.
  • Loi M; Laboratory of Oncology, Istituto Giannina Gaslini, 16147 Genoa, Italy.
  • Emionite L; Animal Facility, IRCCS Azienda Ospedaliera Universitaria San Martino-IST Istituto Nazionale per la Ricerca sul Cancro, 16132 Genoa, Italy.
  • Ognio E; Animal Facility, IRCCS Azienda Ospedaliera Universitaria San Martino-IST Istituto Nazionale per la Ricerca sul Cancro, 16132 Genoa, Italy.
  • Pasparakis M; Institute for Genetics, University of Cologne, 50674 Cologne, Germany; Centre for Molecular Medicine (CMMC), University of Cologne, 50931 Cologne, Germany; Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, 50931 Cologne, Germany.
  • Ribatti D; Department of Basic Medical Sciences, Neurosciences and Sensory Organs, University of Bari Medical School, 70124 Bari, Italy; National Cancer Institute "Giovanni Paolo II", 70124 Bari, Italy.
  • Ponzoni M; Laboratory of Oncology, Istituto Giannina Gaslini, 16147 Genoa, Italy. Electronic address: mircoponzoni@ospedale-gaslini.ge.it.
  • Brignole C; Laboratory of Oncology, Istituto Giannina Gaslini, 16147 Genoa, Italy. Electronic address: chiarabrignole@ospedale-gaslini.ge.it.
J Control Release ; 223: 165-177, 2016 Feb 10.
Article em En | MEDLINE | ID: mdl-26742942
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Melanoma Experimental / Ácido Clodrônico / Macrófagos / Antineoplásicos Idioma: En Ano de publicação: 2016 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Melanoma Experimental / Ácido Clodrônico / Macrófagos / Antineoplásicos Idioma: En Ano de publicação: 2016 Tipo de documento: Article