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Downregulation of Organic Anion Transporting Polypeptide (OATP) 1B1 Transport Function by Lysosomotropic Drug Chloroquine: Implication in OATP-Mediated Drug-Drug Interactions.
Alam, Khondoker; Pahwa, Sonia; Wang, Xueying; Zhang, Pengyue; Ding, Kai; Abuznait, Alaa H; Li, Lang; Yue, Wei.
Afiliação
  • Alam K; Department of Pharmaceutical Sciences, College of Pharmacy, University of Oklahoma Health Sciences Center , Oklahoma City, Oklahoma 73117, United States.
  • Pahwa S; Department of Pharmaceutical Sciences, College of Pharmacy, University of Oklahoma Health Sciences Center , Oklahoma City, Oklahoma 73117, United States.
  • Wang X; Center for Computational Biology and Bioinformatics, Indiana Institute of Personalized Medicine, Department of Medical and Molecular Genetics, Indiana University School of Medicine , Indianapolis, Indiana 46202, United States.
  • Zhang P; Center for Computational Biology and Bioinformatics, Indiana Institute of Personalized Medicine, Department of Medical and Molecular Genetics, Indiana University School of Medicine , Indianapolis, Indiana 46202, United States.
  • Ding K; Department of Biostatistics and Epidemiology, College of Public Health, University of Oklahoma Health Sciences Center , Oklahoma City, Oklahoma 73126, United States.
  • Abuznait AH; Department of Pharmaceutical Sciences, College of Pharmacy, University of Oklahoma Health Sciences Center , Oklahoma City, Oklahoma 73117, United States.
  • Li L; Center for Computational Biology and Bioinformatics, Indiana Institute of Personalized Medicine, Department of Medical and Molecular Genetics, Indiana University School of Medicine , Indianapolis, Indiana 46202, United States.
  • Yue W; Department of Pharmaceutical Sciences, College of Pharmacy, University of Oklahoma Health Sciences Center , Oklahoma City, Oklahoma 73117, United States.
Mol Pharm ; 13(3): 839-51, 2016 Mar 07.
Article em En | MEDLINE | ID: mdl-26750564
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Cloroquina / Regulação da Expressão Gênica / Hepatócitos / Transportador 1 de Ânion Orgânico Específico do Fígado / Interações Medicamentosas / Fígado Idioma: En Ano de publicação: 2016 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Cloroquina / Regulação da Expressão Gênica / Hepatócitos / Transportador 1 de Ânion Orgânico Específico do Fígado / Interações Medicamentosas / Fígado Idioma: En Ano de publicação: 2016 Tipo de documento: Article