Reversible Human TGF-ß Signal Shifting between Tumor Suppression and Fibro-Carcinogenesis: Implications of Smad Phospho-Isoforms for Hepatic Epithelial-Mesenchymal Transitions.

Yoshida, Katsunori; Murata, Miki; Yamaguchi, Takashi; Matsuzaki, Koichi; Okazaki, Kazuichi

Yoshida, Katsunori; Murata, Miki; Yamaguchi, Takashi; Matsuzaki, Koichi; Okazaki, Kazuichi.

Afiliação

Yoshida K; Department of Gastroenterology and Hepatology, Kansai Medical University, 2-5-1, Shin-machi, Hirakata, Osaka 573-1010, Japan. yoshidka@hirakata.kmu.ac.jp.
Murata M; Department of Gastroenterology and Hepatology, Kansai Medical University, 2-5-1, Shin-machi, Hirakata, Osaka 573-1010, Japan. muratami@takii.kmu.ac.jp.
Yamaguchi T; Department of Gastroenterology and Hepatology, Kansai Medical University, 2-5-1, Shin-machi, Hirakata, Osaka 573-1010, Japan. yamaguct@hirakata.kmu.ac.jp.
Matsuzaki K; Department of Gastroenterology and Hepatology, Kansai Medical University, 2-5-1, Shin-machi, Hirakata, Osaka 573-1010, Japan. matsuzak@takii.kmu.ac.jp.
Okazaki K; Department of Gastroenterology and Hepatology, Kansai Medical University, 2-5-1, Shin-machi, Hirakata, Osaka 573-1010, Japan. okazaki@hirakata.kmu.ac.jp.

J Clin Med ; 5(1)2016 Jan 12.

Article em En | MEDLINE | ID: mdl-26771649

Palavras-chave

Smad; epithelial-mesenchymal transition (EMT); hepatic stellate cells (HSC); liver fibro-carcinogenesis; myofibroblast (MFB); transforming growth factor-ß (TGF-ß)

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Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2016 Tipo de documento: Article

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Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2016 Tipo de documento: Article