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Soluble DPP-4 up-regulates toll-like receptors and augments inflammatory reactions, which are ameliorated by vildagliptin or mannose-6-phosphate.
Lee, Dong-Sung; Lee, Eun-Sol; Alam, Md Morshedul; Jang, Jun-Hyeog; Lee, Ho-Sub; Oh, Hyuncheol; Kim, Youn-Chul; Manzoor, Zahid; Koh, Young-Sang; Kang, Dae-Gil; Lee, Dae Ho.
Afiliação
  • Lee DS; Department of Biomedical Chemistry, College of Health and Biomedical Science, Konkuk University, Chung-Ju, 27478, Republic of Korea.
  • Lee ES; College of Human Environmental Sciences, Department of Food Industry Convergence, Wonkwang University, Iksan, 54538, Republic of Korea; Hanbang Body Fluid Research Center, Wonkwang University, Iksan, 54538, Republic of Korea.
  • Alam MM; Tohoku University Graduate School of Medicine, Sendai-shi, 980-8575, Japan.
  • Jang JH; Department of Biochemistry, Inha University School of Medicine, Incheon, 22212, Republic of Korea.
  • Lee HS; Hanbang Body Fluid Research Center, Wonkwang University, Iksan, 54538, Republic of Korea; College of Oriental Medicine and Professional Graduate School of Oriental Medicine, Wonkwang University, Iksan, Jeonbuk, 54538, Republic of Korea.
  • Oh H; Hanbang Body Fluid Research Center, Wonkwang University, Iksan, 54538, Republic of Korea; College of Pharmacy, Wonkwang University, Iksan, 54538, Republic of Korea.
  • Kim YC; College of Human Environmental Sciences, Department of Food Industry Convergence, Wonkwang University, Iksan, 54538, Republic of Korea; Hanbang Body Fluid Research Center, Wonkwang University, Iksan, 54538, Republic of Korea; College of Pharmacy, Wonkwang University, Iksan, 54538, Republic of Korea.
  • Manzoor Z; Department of Microbiology and Immunology, School of Medicine, Jeju National University, Jeju, 690-756, South Korea.
  • Koh YS; Department of Microbiology and Immunology, School of Medicine, Jeju National University, Jeju, 690-756, South Korea.
  • Kang DG; Hanbang Body Fluid Research Center, Wonkwang University, Iksan, 54538, Republic of Korea; College of Oriental Medicine and Professional Graduate School of Oriental Medicine, Wonkwang University, Iksan, Jeonbuk, 54538, Republic of Korea. Electronic address: dgkang@wonkwang.ac.kr.
  • Lee DH; Hanbang Body Fluid Research Center, Wonkwang University, Iksan, 54538, Republic of Korea; Department of Internal Medicine, Wonkwang University School of Medicine and Hospital, Iksan, 54538, Republic of Korea. Electronic address: drhormone@naver.com.
Metabolism ; 65(2): 89-101, 2016 Feb.
Article em En | MEDLINE | ID: mdl-26773932

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pirrolidinas / Adamantano / Dipeptidil Peptidase 4 / Receptores Toll-Like / Inflamação / Manosefosfatos / Nitrilas Idioma: En Ano de publicação: 2016 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pirrolidinas / Adamantano / Dipeptidil Peptidase 4 / Receptores Toll-Like / Inflamação / Manosefosfatos / Nitrilas Idioma: En Ano de publicação: 2016 Tipo de documento: Article