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Identification of a Small Molecule Inhibitor of RAD52 by Structure-Based Selection.
Sullivan, Katherine; Cramer-Morales, Kimberly; McElroy, Daniel L; Ostrov, David A; Haas, Kimberly; Childers, Wayne; Hromas, Robert; Skorski, Tomasz.
Afiliação
  • Sullivan K; Department of Microbiology and Immunology and Fels Institute for Cancer Research and Molecular Biology, Temple University School of Medicine, Philadelphia, Pennsylvania 19140, United States of America.
  • Cramer-Morales K; Department of Microbiology and Immunology and Fels Institute for Cancer Research and Molecular Biology, Temple University School of Medicine, Philadelphia, Pennsylvania 19140, United States of America.
  • McElroy DL; Department of Pathology, Immunology and Laboratory Medicine, College of Medicine, University of Florida & Shands, Gainesville, Florida 32610, United States of America.
  • Ostrov DA; Department of Pathology, Immunology and Laboratory Medicine, College of Medicine, University of Florida & Shands, Gainesville, Florida 32610, United States of America.
  • Haas K; Moulder Center for Drug Discovery Research, Temple University School of Pharmacy, Philadelphia, Pennsylvania 19140, United States of America.
  • Childers W; Moulder Center for Drug Discovery Research, Temple University School of Pharmacy, Philadelphia, Pennsylvania 19140, United States of America.
  • Hromas R; Department of Medicine, College of Medicine, University of Florida & Shands, Gainesville, Florida 32610, United States of America.
  • Skorski T; Department of Microbiology and Immunology and Fels Institute for Cancer Research and Molecular Biology, Temple University School of Medicine, Philadelphia, Pennsylvania 19140, United States of America.
PLoS One ; 11(1): e0147230, 2016.
Article em En | MEDLINE | ID: mdl-26784987
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias da Mama / DNA de Cadeia Simples / Proteína Rad52 de Recombinação e Reparo de DNA / Bibliotecas de Moléculas Pequenas Idioma: En Ano de publicação: 2016 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias da Mama / DNA de Cadeia Simples / Proteína Rad52 de Recombinação e Reparo de DNA / Bibliotecas de Moléculas Pequenas Idioma: En Ano de publicação: 2016 Tipo de documento: Article